Assessing and advancing the safety of CRISPR-Cas tools: from DNA to RNA editing
CRISPR-Cas gene editing has revolutionized experimental molecular biology over the past
decade and holds great promise for the treatment of human genetic diseases. Here we …
decade and holds great promise for the treatment of human genetic diseases. Here we …
Advances in nucleic acid amplification techniques (NAATs): COVID-19 point-of-care diagnostics as an example
Achieving superhigh sensitivity is the ultimate goal for bio-detection in modern analytical
science and life science. Among variable signal amplification strategies, nucleic acid …
science and life science. Among variable signal amplification strategies, nucleic acid …
CRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules
W Feng, AM Newbigging, J Tao, Y Cao, H Peng… - Chemical …, 2021 - pubs.rsc.org
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-
associated (Cas) protein systems have transformed the field of genome editing and …
associated (Cas) protein systems have transformed the field of genome editing and …
Clustered regularly interspaced short palindromic repeats/Cas9-mediated lateral flow nucleic acid assay
X Wang, E Xiong, T Tian, M Cheng, W Lin, H Wang… - ACS …, 2020 - ACS Publications
The lateral flow assay is one of the most convenient analytical techniques for analyzing the
immune response, but its applicability to precise genetic analyses is limited by the false …
immune response, but its applicability to precise genetic analyses is limited by the false …
CRISPR-based detection of SARS-CoV-2: A review from sample to result
The current pandemic of the 2019 novel coronavirus (COVID-19) caused by SARS-CoV-2
(severe acute respiratory syndrome coronavirus-2) has raised significant public health …
(severe acute respiratory syndrome coronavirus-2) has raised significant public health …
Signal amplification and output of CRISPR/Cas-based biosensing systems: A review
SY Wang, YC Du, DX Wang, JY Ma, AN Tang… - Analytica Chimica …, 2021 - Elsevier
CRISPR (clustered regularly interspaced short palindromic repeats)/Cas (CRISPR-
associated) proteins are powerful gene-editing tools because of their ability to accurately …
associated) proteins are powerful gene-editing tools because of their ability to accurately …
[HTML][HTML] CRISPR–Cas: a tool for cancer research and therapeutics
In the past decade, the development of a genome-editing technology mediated by CRISPR
has made genetic engineering easier than ever, both in vitro and in vivo. CRISPR systems …
has made genetic engineering easier than ever, both in vitro and in vivo. CRISPR systems …
CRISPR/Cas12a-mediated gold nanoparticle aggregation for colorimetric detection of SARS-CoV-2
The trans-cleavage activity of the target-activated CRISPR/Cas12a liberated an RNA
crosslinker from a molecular transducer, which facilitated the assembly of gold …
crosslinker from a molecular transducer, which facilitated the assembly of gold …
Advances in clustered, regularly interspaced short palindromic repeats (CRISPR)-based diagnostic assays assisted by micro/nanotechnologies
Clustered, regularly interspaced short palindromic repeats (CRISPR)-based diagnoses,
derived from gene-editing technology, have been exploited for less than 5 years and are …
derived from gene-editing technology, have been exploited for less than 5 years and are …
Argonaute integrated single-tube PCR system enables supersensitive detection of rare mutations
Q Liu, X Guo, G Xun, Z Li, Y Chong, L Yang… - Nucleic acids …, 2021 - academic.oup.com
Technological advances in rare DNA mutations detection have revolutionized the diagnosis
and monitoring of tumors, but they are still limited by the lack of supersensitive and high …
and monitoring of tumors, but they are still limited by the lack of supersensitive and high …