Nanoparticles for cancer therapy: a review of influencing factors and evaluation methods for biosafety

J Li, T Wu, S Li, X Chen, Z Deng, Y Huang - Clinical And Translational …, 2023 - Springer
Nanoparticles are widely used in the biomedical field for diagnostic and therapeutic
purposes due to their small size, high carrier capacity, and ease of modification, which …

Mannosylated poly (acrylic acid)-coated mesoporous silica nanoparticles for anticancer therapy

H Lee, M Choi, HE Kim, M Jin, WJ Jeon, M Jung… - Journal of Controlled …, 2022 - Elsevier
Although mesoporous silica nanoparticles (MSNs) are widely used as anticancer drug
carriers, unmodified MSNs induce off-target effects and at high doses, there are adverse …

Boronates as hydrogen peroxide–reactive warheads in the design of detection probes, prodrugs, and nanomedicines used in tumors and other diseases

JW Chen, TC Wu, W Liang, JJ Ciou, CH Lai - Drug Delivery and …, 2023 - Springer
Abstract Hydrogen peroxide (H2O2) has always been a topic of great interests attributed to
its vital role in biological process. H2O2 is known as a major reactive oxygen species (ROS) …

Enhanced bactericidal and in vivo wound healing potential of biosynthesized zinc oxide nanoparticles from psyllium mucilage

A Azam, G Muhammad, MS Aslam… - Applied …, 2023 - Wiley Online Library
The multifunctional zinc oxide nanoparticles are synthesized using a cost‐effective, efficient,
eco‐friendly, simple, and clean synthesis approach. Herein, we reported the antibacterial …

Fabrication of magnetic nanocomposite as responsive drug delivery vehicle for cervical cancer therapy

M Darroudi, SE Nazari, M Karimzadeh… - Applied …, 2023 - Wiley Online Library
The development of carriers for drug delivery faces significant challenges from a therapeutic
perspective. The present study presents an innovative nanocarrier based on combination of …

Mannoside-functionalized silica nanocomposite-encapsulated doxorubicin for mda-mb-231 cancer cell targeting and delivery

YH Su, HC Lin, HY Li, CH Lien, YH Shih… - ACS Applied Nano …, 2023 - ACS Publications
The purpose of this study was to develop a carbohydrate silica nanocomposite, M-mDOX@
SiO2, that can specifically target cancer cells and release the drug doxorubicin (DOX) …

Synthesis of a Multifunctional Glyco-Block Copolymer through Reversible Addition–Fragmentation Chain Transfer Polymerization and Click Chemistry for Enzyme and …

TC Wu, CL Lai, G Sivakumar, YH Huang… - ACS Applied Materials …, 2023 - ACS Publications
Reversible addition–fragmentation chain transfer polymerization has been used in various
applications such as preparing nanoparticles, stimulus-responsive polymers, and hydrogels …

Sulfation of Heparan and Chondroitin Sulfate Ligands Enables Cell‐Specific Homing of Nanoprobes

S Mardhekar, B Subramani, P Samudra… - … A European Journal, 2023 - Wiley Online Library
Demystifying the sulfation code of glycosaminoglycans (GAGs) to induce precise homing of
nanoparticles in tumor cells or neurons influences the development of a potential drug‐or …

AuAg nanocomposites suppress biofilm-induced inflammation in human osteoblasts

CW Lee, ZC Lin, YC Chiang, SY Li, JJ Ciou… - …, 2023 - iopscience.iop.org
Staphylococcus aureus (S. aureus) forms biofilm that causes periprosthetic joint infections
and osteomyelitis (OM) which are the intractable health problems in clinics. The silver …

Synthesis of multi-functional nano-vectors for target-specific drug delivery

TC Wu, PY Lee, CL Lai, CH Lai - Polymers, 2021 - mdpi.com
Magnetic nanoparticles have gained attention in cancer therapy due to their non-toxic
properties and high bio-compatibility. In this report, we synthesize a dual-responsive …