Cardiovascular diseases are the most prominent maladies in aging societies. Indeed, aging
promotes the structural and functional declines of both the heart and the blood circulation …

Biological sex is an important modifier of physiology and influences pathobiology in many
diseases. While heart disease is the number one cause of death worldwide in both men and …

Aging leads to increased cellular senescence and is associated with decreased potency of
tissue‐specific stem/progenitor cells. Here, we have done an extensive analysis of cardiac …

Abstract “Inside every old person is a young person wondering what happened.” So, what is
aging? Aging is a manifestation of progressive, time-dependent failure of molecular …

Cardiac ageing manifests as a decline in function leading to heart failure. At the cellular
level, ageing entails decreased replicative capacity and dysregulation of cellular processes …

The knowledge that advanced age is a major risk factor for cardiovascular disease (CVD)
has stimulated interest in cardiac aging. Understanding how the heart remodels with age …

Heart failure is a systemic syndrome caused by multiple pathological factors. Current
treatments do not have satisfactory outcomes. Several basic studies have revealed the …

Cardiovascular diseases increase dramatically with age in both men and women. While it is
clear that advanced age allows more time for individuals to be exposed to risk factors in …

Diabetic cardiomyopathy (DCM) was first recognized more than four decades ago and
occurred independent of cardiovascular diseases or hypertension in both type 1 and type 2 …

Aging is a continuous and irreversible process that leads to a progressive deterioration in
cardiac geometry and function. Klotho is an anti-aging protein with cardioprotective effect …