Platelets produce platelet growth factors such as PDGF, IGF-1, EGF-, HGF, TGFβ, bFGF, and
VEGF, which are crucial in regulating all stages of the wound healing process. The source of …

Premature ovarian insufficiency (POI) occurs in at least 1% of all women and causes life-
long health problems and psychological stress. Infertility caused by POI used to be …

Importance Approximately 3.4% of adults have ankle (tibiotalar) osteoarthritis and, among
younger patients, ankle osteoarthritis is more common than knee and hip osteoarthritis. Few …

Abstract Purpose of Review This review evaluates current clinical literature on the use of
platelet-rich plasma (PRP), including leukocyte-rich PRP (LR-PRP) and leukocyte-poor PRP …

The clinical application of platelet-rich plasma (PRP) and other regenerative therapies in
sports, spine, and musculoskeletal medicine has soared in the last decade. Over this period …

Background/aim Significant biological differences in platelet-rich plasma (PRP) preparations
have been highlighted and could explain the large variability in the clinical benefit of PRP …

Satellite cells are tissue resident muscle stem cells required for postnatal skeletal muscle
growth and repair through replacement of damaged myofibers. Muscle regeneration is …

Background Platelet-rich plasma (PRP) therapy has become an increasingly popular
treatment for orthopaedics and sports-related injuries, and various clinically available PRP …

Background Muscle lesions account for one-third of sport-related injuries, thus representing
a substantial problem for both players and their teams. The use of platelet-rich plasma (PRP) …

Background To evaluate the efficacy of a single platelet-rich plasma (PRP) injection in
reducing the return to sport duration in male athletes, following an acute hamstring injury …