Natural products: An upcoming therapeutic approach to cancer

S Dutta, S Mahalanobish, S Saha, S Ghosh… - Food and Chemical …, 2019 - Elsevier
Cancer is one of the leading causes of death across the world. Different environmental and
anthropogenic factors initiate mutations in different functional genes of growth factors and …

Conversion of extracellular ATP into adenosine: a master switch in renal health and disease

KM Dwyer, BK Kishore, SC Robson - Nature Reviews Nephrology, 2020 - nature.com
ATP and its ultimate degradation product adenosine are potent extracellular signalling
molecules that elicit a variety of pathophysiological functions in the kidney through the …

[HTML][HTML] Inhibition of Brd4 alleviates renal ischemia/reperfusion injury-induced apoptosis and endoplasmic reticulum stress by blocking FoxO4-mediated oxidative …

H Liu, L Wang, X Weng, H Chen, Y Du, C Diao, Z Chen… - Redox biology, 2019 - Elsevier
Ischemia/reperfusion injury (I/R) is one of the leading causes of acute kidney injury (AKI) that
typically occurs in renal surgeries. However, renal I/R still currently lacks effective …

The effects and mechanisms of cyanidin-3-glucoside and its phenolic metabolites in maintaining intestinal integrity

J Tan, Y Li, DX Hou, S Wu - Antioxidants, 2019 - mdpi.com
Cyanidin-3-glucoside (C3G) is a well-known natural anthocyanin and possesses antioxidant
and anti-inflammatory properties. The catabolism of C3G in the gastrointestinal tract could …

Ferulic acid protects against methotrexate nephrotoxicity via activation of Nrf2/ARE/HO-1 signaling and PPARγ, and suppression of NF-κB/NLRP3 inflammasome axis

AM Mahmoud, OE Hussein, SM Abd El-Twab… - Food & Function, 2019 - pubs.rsc.org
Drug-induced nephrotoxicity contributes to acute kidney injury (AKI) and represents a major
problem in the clinical setting. We investigated the possible involvement of NLRP3 …

Ferulic acid nanocapsules as a promising treatment modality for colorectal cancer: Preparation and in vitro/in vivo appraisal

RI El-Gogary, M Nasr, LA Rahsed, MA Hamzawy - Life sciences, 2022 - Elsevier
Aims Ferulic acid is a polyphenolic compound with proven anticancer properties, but it
suffers from low solubility and bioavailability. In the current work, polymeric and lipidic …

Adenosine at the interphase of hypoxia and inflammation in lung injury

X Li, NK Berg, T Mills, K Zhang, HK Eltzschig… - Frontiers in …, 2021 - frontiersin.org
Hypoxia and inflammation often coincide in pathogenic conditions such as acute respiratory
distress syndrome (ARDS) and chronic lung diseases, which are significant contributors to …

The role of TRPC6 in renal ischemia/reperfusion and cellular hypoxia/reoxygenation injuries

X Hou, M Huang, X Zeng, Y Zhang, A Sun… - Frontiers in Molecular …, 2021 - frontiersin.org
Renal ischemia/reperfusion (I/R), a major cause of acute kidney injury (AKI), is a serious
clinical event in patients during post-renal transplantation. I/R is associated with renal …

Improvement of germinated brown rice quality with autoclaving treatment

C Ren, B Hong, X Zheng, L Wang… - Food Science & …, 2020 - Wiley Online Library
Germinated brown rice (GBR) is a popular functional food containing considerable amounts
of beneficial nutrients and bioactive compounds. Here, autoclaving at 115° C for 20 min was …

Remdesivir alleviates acute kidney injury by inhibiting the activation of NLRP3 inflammasome

L Yin, H Zhao, H Zhang, Y Li, Y Dong, H Ju… - Frontiers in …, 2021 - frontiersin.org
Acute kidney injury (AKI) is a frequent clinical complication in critically ill patients, and it
rapidly develops into renal failure with high morbidity and mortality. However, other than …