Microphysiological systems (MPS) are drawing increasing interest from academia and from
biomedical industry due to their improved capability to capture human physiology. MPS offer …

Mechanical stretch plays an important role in the control of cardiomyocyte behavior, as well
as in the study of the mechanisms of cardiovascular function and pathology. The complexity …

The application of biomimetic physical stimuli replicating the in vivo dynamic
microenvironment is crucial for the in vitro development of functional cardiac tissues. In …

Cardiovascular diseases are the leading cause of global mortality and reduced quality of
life. Human-induced pluripotent stem cells-derived cardiomyocytes (hiPSC-CMs) provide a …

Cardiovascular diseases bear strong socioeconomic and ecological impact on the
worldwide healthcare system. A large consumption of goods, use of polymer-based …

Electro-mechanical co-stimulation of cells can be a useful cue for tissue engineering.
However, reliable co-stimulation platforms still have limitations due to low durability of the …

Human iPSC-derived cardiomyocytes (hiPSC-CMs) exhibit functional immaturity, potentially
impacting their suitability for assessing drug proarrhythmic potential. We previously devised …

Neuromuscular electrical stimulation (NMES) is often used to increase muscle strength and
functionality. Muscle architecture is important for the skeletal muscle functionality. The aim of …

Background The use of human induced pluripotent stem cells (hiPSCs) is attracting attention
as a potential personalized therapy for damaged myocardium, as they are accessible and …

La cardiopatía isquémica es una afección del corazón que se origina por la disminución o
interrupción del flujo sanguíneo en las arterias coronarias. En la mayoría de los casos la …