Chronic lymphocytic leukaemia
Chronic lymphocytic leukaemia (CLL) is a malignancy of CD5+ B cells that is characterized
by the accumulation of small, mature-appearing lymphocytes in the blood, marrow and …
by the accumulation of small, mature-appearing lymphocytes in the blood, marrow and …
Infections in patients with chronic lymphocytic leukaemia: mitigating risk in the era of targeted therapies
Chronic lymphocytic leukaemia (CLL) is the most common leukaemia with infections a
leading cause of morbidity and mortality. Recently there has been a paradigm shift from the …
leading cause of morbidity and mortality. Recently there has been a paradigm shift from the …
Idelalisib or placebo in combination with bendamustine and rituximab in patients with relapsed or refractory chronic lymphocytic leukaemia: interim results from a …
AD Zelenetz, JC Barrientos, JR Brown… - The Lancet …, 2017 - thelancet.com
Background Bendamustine plus rituximab is a standard of care for the management of
patients with relapsed or refractory chronic lymphocytic leukaemia. New therapies are …
patients with relapsed or refractory chronic lymphocytic leukaemia. New therapies are …
Specific Requirement of the p84/p110γ Complex of PI3Kγ for Antibody‐Activated, Inducible Cross‐Presentation in Murine Type 2 DCs
D Koumantou, AC Adiko, P Bourdely… - Advanced …, 2024 - Wiley Online Library
Cross‐presentation by MHCI is optimally efficient in type 1 dendritic cells (DC) due to their
high capacity for antigen processing. However, through specific pathways, other DCs, such …
high capacity for antigen processing. However, through specific pathways, other DCs, such …
Minimizing and managing treatment-associated complications in patients with chronic lymphocytic leukemia
E Iskierka-Jażdżewska, T Robak - Expert Review of Hematology, 2020 - Taylor & Francis
Introduction: During recent years, therapy in chronic lymphocytic leukemia (CLL) has
changed dramatically. The introduction of small molecule inhibitors has shown remarkable …
changed dramatically. The introduction of small molecule inhibitors has shown remarkable …
Idelalisib therapy of indolent B-cell malignancies: chronic lymphocytic leukemia and small lymphocytic or follicular lymphomas
YF Madanat, MR Smith, A Almasan… - Blood and lymphatic …, 2016 - Taylor & Francis
Chronic lymphocytic leukemia, small lymphocytic lymphoma, and follicular lymphoma are
indolent B-cell lymphoproliferative disorders that mainly affect an older population. Although …
indolent B-cell lymphoproliferative disorders that mainly affect an older population. Although …
B cell receptor signaling drives APOBEC3 expression via direct enhancer regulation in chronic lymphocytic leukemia B cells
Constitutively activated B cell receptor (BCR) signaling is a primary biological feature of
chronic lymphocytic leukemia (CLL). The biological events controlled by BCR signaling in …
chronic lymphocytic leukemia (CLL). The biological events controlled by BCR signaling in …
Magic pills: new oral drugs to treat chronic lymphocytic leukemia
C Vitale, V Griggio, M Todaro, C Salvetti… - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: A deeper understanding of chronic lymphocytic leukemia (CLL) biology has led
to the identification of new promising therapeutic targets. Different classes of molecules are …
to the identification of new promising therapeutic targets. Different classes of molecules are …
Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells
BD Hock, SA MacPherson, JL McKenzie - PLoS One, 2017 - journals.plos.org
Chronic lymphocytic leukemia (CLL) is associated with T cell dysfunction. Activated CLL
cells are found within the lymphoid tumor micro-environment and overcoming immuno …
cells are found within the lymphoid tumor micro-environment and overcoming immuno …
淋巴瘤和cAMP 信号通路
钟瑶， 朱琦 - 中国癌症杂志, 2016 - china-oncology.com
淋巴瘤细胞克隆性增殖和疾病进展涉及细胞内多个信号通路. 环腺苷酸(cyclic adenosine
monophosphate, cAMP) 信号通路作为一种重要的细胞内信息传递系统参与细胞增殖, 分泌 …
monophosphate, cAMP) 信号通路作为一种重要的细胞内信息传递系统参与细胞增殖, 分泌 …