Medicinal chemistry and biomedical applications of bismuth-based compounds and nanoparticles

DM Griffith, H Li, MV Werrett, PC Andrews… - Chemical Society …, 2021 - pubs.rsc.org
Bismuth as a relatively non-toxic and inexpensive metal with exceptional properties has
numerous biomedical applications. Bismuth-based compounds are used extensively as …

Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Y Pan, W Tang, W Fan, J Zhang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

[HTML][HTML] Nanomaterial-based CT contrast agents and their applications in image-guided therapy

Z Jiang, M Zhang, P Li, Y Wang, Q Fu - Theranostics, 2023 - ncbi.nlm.nih.gov
Computed tomography (CT), a diagnostic tool with clinical application, comprehensive
coverage, and low cost, is used in hospitals worldwide. However, CT imaging fails to …

On-demand generation of peroxynitrite from an integrated two-dimensional system for enhanced tumor therapy

S Liu, W Li, H Chen, J Zhou, S Dong, P Zang, B Tian… - ACS …, 2022 - ACS Publications
Nanosystem-mediated tumor radiosensitization strategy combining the features of X-ray with
infinite penetration depth and high atomic number elements shows considerable application …

Targeted CuFe2O4 hybrid nanoradiosensitizers for synchronous chemoradiotherapy

M Salehiabar, M Ghaffarlou, A Mohammadi… - Journal of Controlled …, 2023 - Elsevier
Multifunctional nanoplatforms based on novel bimetallic nanoparticles have emerged as
effective radiosensitizers owing to their potential capability in cancer cells radiosensitization …

Tailoring silica-based nanoscintillators for peroxynitrite-potentiated nitrosative stress in postoperative radiotherapy of colon cancer

S Liu, W Li, Y Zhang, J Zhou, Y Du, S Dong, B Tian… - Nano Letters, 2022 - ACS Publications
The development of a manageable reactive nitrogen species-potentiated nitrosative stress
induction system for cancer therapy has remained elusive. Herein, tailored silica-based …

Recent progress in nitric oxide-generating nanomedicine for cancer therapy

Y Li, B Yoon, A Dey, JH Park - Journal of Controlled Release, 2022 - Elsevier
Nitric oxide (NO) is an endogenous, multipotent biological signaling molecule that
participates in several physiological processes. Recently, exogenous supplementation of …

[HTML][HTML] Peroxidase-mimicking TA-VOx nanobranches for enhanced photothermal/chemodynamic therapy of glioma by inhibiting the expression of HSP60

Q Guo, M Yin, J Fan, Y Yang, T Liu, H Qian, X Dai… - Materials & Design, 2022 - Elsevier
Glioblastoma multiforme (GBM) is the most prevalent malignant brain tumor. It expresses
high levels of heat shock protein (HSP60), which is associated with poor prognosis …

The promise of nanoparticles-based radiotherapy in cancer treatment

M Haque, MS Shakil, KM Mahmud - Cancers, 2023 - mdpi.com
Simple Summary Radiotherapy (RT) is used worldwide as a gold standard treatment
approach for cancer management. However, the RT treatment modality contains limitations …

Novel gas‐based nanomedicines for cancer therapy

X Yao, B Yang, J Xu, Q He, W Yang - View, 2022 - Wiley Online Library
Gas therapy, an emerging cancer treatment method of inflammation‐related diseases, has
recently received substantial attention. The rapid advances in nanomedicine and …