Diastereoselective synthesis of 2,5-disubstituted tetrahydrofurans - ScienceDirect Skip to main
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Many natural products incorporate tetrahydrofuran (THF) moieties, including macrolides, 1
polyether ionophores, 2 acetogenins 3 or oxidized lipids, 4 with a wide array of bioactivities …

Temporary silicon‐tethered ring‐closing metathesis represents an important cross‐coupling
strategy for the formation of medium‐sized silacycles. These intermediates are valuable …

Deoxygenations of alcohols, ie, processes that replace a hydroxyl group with hydrogen at a
saturated carbon, find applications in both total synthesis and the systematic modifications of …

This personal account provides an overview of work conducted in my research group, and
through collaborations with other chemists and engineers, to develop flow electrolysis cells …

Efficient nickel-catalyzed stereoselective asymmetric intramolecular reductive cyclization of
O-alkynones is reported. A P-chiral bisphosphine ligand DI-BIDIME was found to be effective …

The synthesis of the subgroups of acetogenins containing non-adjacent bis-THF and non-
adjacent THF-THP core units is reviewed. Specifically, total syntheses of gigantecin, 4 …

This is a review of papers published in the year 2008 that focus on the synthesis, reactivity,
or properties of compounds containing a carbon-transition metal double or triple bond.

cis-2, 5-Disubstituted tetrahydrofurans constitute the core of several natural products and
synthetic analogues which exhibit a broad and interesting range of biological activities. This …

Two concise syntheses of the natural products cis-sylvaticin and sylvaticin are reported,
using oxidative cyclization methodology as the key step. A sequential solvolysis/hydride …