Neurons have long held the spotlight as the central players of the nervous system, but we
must remember that we have equal numbers of astrocytes and neurons in the brain. Are …

The function and efficacy of synaptic transmission are determined not only by the
composition and activity of pre‐and postsynaptic components but also by the environment in …

We demonstrate an integrated approach to build, test, and refine a model of a cellular
pathway, in which perturbations to critical pathway components are analyzed using DNA …

Mature protoplasmic astrocytes exhibit an extremely dense ramification of fine processes,
yielding a 'spongiform'morphology. This complex morphology enables protoplasmic …

Astrocytes are thought to play a variety of key roles in the adult brain, such as their
participation in synaptic transmission, in wound healing upon brain injury, and adult …

Neuronal migration is a fundamental process in central nervous system (CNS) development.
The assembly of functioning neuronal circuits relies on neuronal migration occurring in the …

Glial cells express a variety of neurotransmitter receptors. Notably, Bergmann glial cells in
the cerebellum have Ca2+-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic …

2-Arachidonoyl-glycerol (2-AG) is an endocannabinoid that is released from postsynaptic
neurons, acts retrogradely on presynaptic cannabinoid receptor CB1, and induces short-and …

Foliation of the mouse cerebellum occurs primarily during the first 2 weeks after birth and is
accompanied by tremendous proliferation of granule cell precursors (GCPs). We have …

In many areas of the vertebrate brain, such as the cerebral and cerebellar cortices, neural
circuits rely on inhibition mediated by GABA (γ-aminobutyric acid) to shape the …