Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures
Inflammatory bowel diseases (IBDs), eg, Crohn's disease (CD) and ulcerative colitis (UC),
are chronic immune-mediated inflammatory diseases. A comprehensive overview of an IBD …
are chronic immune-mediated inflammatory diseases. A comprehensive overview of an IBD …
Exploring immunome and microbiome interplay in reproductive health: current knowledge, challenges, and novel diagnostic tools
The dynamic interplay between the immunome and microbiome in reproductive health is a
complex and rapidly advancing research field, holding tremendously vast possibilities for the …
complex and rapidly advancing research field, holding tremendously vast possibilities for the …
[HTML][HTML] Phage immunoprecipitation and sequencing—a versatile technique for mapping the antibody reactome
GN Sundell, SC Tao - Molecular & Cellular Proteomics, 2024 - Elsevier
Characterizing the antibody reactome for circulating antibodies provide insight into
pathogen exposure, allergies and autoimmune diseases. This is important for biomarker …
pathogen exposure, allergies and autoimmune diseases. This is important for biomarker …
Systemic antibody responses against gut microbiota flagellins implicate shared and divergent immune reactivity in Crohn's disease and chronic fatigue syndrome
AR Bourgonje, NV Hörstke, M Fehringer, G Innocenti… - Microbiome, 2024 - Springer
Background Elevated systemic antibody responses against gut microbiota flagellins are
observed in both Crohn's disease (CD) and myalgic encephalomyelitis/chronic fatigue …
observed in both Crohn's disease (CD) and myalgic encephalomyelitis/chronic fatigue …
[HTML][HTML] Untangling associations between immunoglobulin genotypes, repertoires and function
Immunoglobulin (IG) genes, encoding B cell receptors (BCRs), are fundamental components
of the mammalian immune system, which evolved to recognize the diverse antigenic …
of the mammalian immune system, which evolved to recognize the diverse antigenic …
Maintenance of caecal homeostasis by diverse adaptive immune cells in the rhesus macaque
X Castro Dopico, M Guryleva… - Clinical & …, 2024 - Wiley Online Library
Objectives The caecum bridges the small and large intestine and plays a front‐line role in
discriminating gastrointestinal antigens. Although dysregulated in acute and chronic …
discriminating gastrointestinal antigens. Although dysregulated in acute and chronic …
[HTML][HTML] Differential effects of heating modes on the immunogenic potential of soy-derived peptides released after in vitro infant digestion
J Tang, S Boeren, HJ Wichers, KA Hettinga - Food Research International, 2024 - Elsevier
During production of soy-based infant formula, soy protein undergoes heating processes.
This study investigated the differential impact of heating modes on the immunogenic …
This study investigated the differential impact of heating modes on the immunogenic …
Antibody signatures against viruses and microbiome reflect past and chronic exposures and associate with aging and inflammation
S Andreu-Sánchez, A Ripoll-Cladellas, A Culinscaia… - Iscience, 2024 - cell.com
Encounters with pathogens and other molecules can imprint long-lasting effects on our
immune system, influencing future physiological outcomes. Given the wide range of …
immune system, influencing future physiological outcomes. Given the wide range of …
Linear epitopes of bony fish β-parvalbumins
E Franciskovic, L Thörnqvist, L Greiff, M Gasset… - Frontiers in …, 2024 - frontiersin.org
Introduction Fish β-parvalbumins are common targets of allergy-causing immunity. The
nature of antibody responses to such allergens determines the biological outcome following …
nature of antibody responses to such allergens determines the biological outcome following …
Phage Immunoprecipitation Sequencing (PhIP-Seq) for Analyzing Antibody Epitope Repertoires Against Food Antigens
I Filimonova, G Innocenti, T Vogl - Food Allergens: Methods and Protocols, 2023 - Springer
While thousands of food and environmental allergens have been reported, conventional
methods for allergy testing typically rely on measuring immunoglobulin E (IgE) binding …
methods for allergy testing typically rely on measuring immunoglobulin E (IgE) binding …