Disease manifestations and pathogenic mechanisms of group A Streptococcus

MJ Walker, TC Barnett, JD McArthur… - Clinical microbiology …, 2014 - Am Soc Microbiol
Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …

Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria

LA Marraffini, AC DeDent… - … and molecular biology …, 2006 - Am Soc Microbiol
The cell wall envelopes of gram-positive bacteria represent a surface organelle that not only
functions as a cytoskeletal element but also promotes interactions between bacteria and …

Large‐scale identification of serotype 4 Streptococcus pneumoniae virulence factors

DL Hava, A Camilli - Molecular microbiology, 2002 - Wiley Online Library
Streptococcus pneumoniae (the pneumococcus) is carried in the nasopharynx of healthy
individuals, but can spread to other host sites and lead to pneumonia, bacteraemia, otitis …

Assembly of pili on the surface of Corynebacterium diphtheriae

H Ton‐That, O Schneewind - Molecular microbiology, 2003 - Wiley Online Library
Pili of Gram‐negative pathogens are formed from pilin precursor molecules by non‐covalent
association within the outer membrane envelope. Gram‐positive microbes employ the cell …

Crystal structures of Staphylococcus aureus sortase A and its substrate complex

Y Zong, TW Bice, H Ton-That, O Schneewind… - Journal of Biological …, 2004 - ASBMB
The cell wall envelope of staphylococci and other Gram-positive pathogens is coated with
surface proteins that interact with human host tissues. Surface proteins of Staphylococcus …

Surface proteins of gram-positive bacteria and how they get there

JR Scott, TC Barnett - Annu. Rev. Microbiol., 2006 - annualreviews.org
Surface proteins are critical in determining the identifying characteristics of individual
bacteria and their interaction with the environment. Because the structure of the cell surface …

Streptococcus pyogenes adhesion and colonization

S Brouwer, TC Barnett, T Rivera‐Hernandez… - FEBS …, 2016 - Wiley Online Library
Streptococcus pyogenes (group A Streptococcus, GAS) is a human‐adapted pathogen
responsible for a wide spectrum of disease. GAS can cause relatively mild illnesses, such as …

[HTML][HTML] Protein sorting to the cell wall envelope of Gram-positive bacteria

H Ton-That, LA Marraffini, O Schneewind - Biochimica et Biophysica Acta …, 2004 - Elsevier
The covalent anchoring of surface proteins to the cell wall envelope of Gram-positive
bacteria occurs by a universal mechanism requiring sortases, extracellular transpeptidases …

Assembly and role of pili in group B streptococci

S Dramsi, E Caliot, I Bonne, S Guadagnini… - Molecular …, 2006 - Wiley Online Library
Streptococcus agalactiae [group B streptococcus (GBS)] is the leading cause of neonatal
pneumonia, sepsis and meningitis. An in silico genome analysis indicated that GBS strain …

Assembly of pili in Gram-positive bacteria

H Ton-That, O Schneewind - Trends in microbiology, 2004 - cell.com
The formation of adhesive pili on the surface of Gram-negative bacteria has been studied in
detail, whereas the pilus assembly pathways in Gram-positive bacteria remain to be …