Nucleoside/nucleotide analogues in the treatment of chronic hepatitis B
The current available agents for the treatment of chronic hepatitis B (CHB) include
immunomodulatory agents, such as interferon-α and pegylated interferon-α, and oral …
immunomodulatory agents, such as interferon-α and pegylated interferon-α, and oral …
The role of hepatitis B virus integrations in the pathogenesis of human hepatocellular carcinoma
RB Guerrero, LR Roberts - Journal of hepatology, 2005 - Elsevier
Hepatocellular carcinoma (HCC) is a leading cause of cancer death world wide, accounting
for approximately 600,000 deaths per year [1–4]. In North America, Western Europe and …
for approximately 600,000 deaths per year [1–4]. In North America, Western Europe and …
An efficient antiviral strategy for targeting hepatitis B virus genome using transcription activator-like effector nucleases
J Chen, W Zhang, J Lin, F Wang, M Wu, C Chen… - Molecular Therapy, 2014 - cell.com
The hepatitis B virus (HBV) is a DNA virus that can cause chronic hepatitis B (CHB) in
humans. Current therapies for CHB infection are limited in efficacy and do not target the pre …
humans. Current therapies for CHB infection are limited in efficacy and do not target the pre …
Molecular evolution of hepatitis B virus over 25 years
C Osiowy, E Giles, Y Tanaka, M Mizokami… - Journal of …, 2006 - Am Soc Microbiol
Determining the longitudinal molecular evolution of hepatitis B virus (HBV) is difficult due to
HBV's genomic complexity and the need to study paired samples collected over long …
HBV's genomic complexity and the need to study paired samples collected over long …
Antiviral efficacy and host immune response induction during sequential treatment with SB 9200 followed by entecavir in woodchucks
M Suresh, KE Korolowicz, M Balarezo, RP Iyer… - PLoS …, 2017 - journals.plos.org
SB 9200, an orally bioavailable dinucleotide, activates the viral sensor proteins, retinoic acid-
inducible gene 1 (RIG-I) and nucleotide-binding oligomerization domain-containing protein …
inducible gene 1 (RIG-I) and nucleotide-binding oligomerization domain-containing protein …
Hepatitis B and C viruses in infants and young children
MK Slowik, R Jhaveri - Seminars in pediatric infectious diseases, 2005 - Elsevier
Advances during the past 20 years have led to a better understanding of the prevention,
diagnosis, and treatment of acute and chronic hepatitis B (HBV) and hepatitis C (HCV) …
diagnosis, and treatment of acute and chronic hepatitis B (HBV) and hepatitis C (HCV) …
Perioperative predictors of outcome of hepatectomy for HBV-related hepatocellular carcinoma
Z He, D Tang - Frontiers in Oncology, 2023 - frontiersin.org
Hepatitis B virus (HBV) is identified as a major risk factor for hepatocellular carcinoma
(HCC), resulting in so-called hepatitis B virus-related hepatocellular carcinoma (HBV-related …
(HCC), resulting in so-called hepatitis B virus-related hepatocellular carcinoma (HBV-related …
Persistent infection of hepatitis B virus is involved in high rate of p16 methylation in hepatocellular carcinoma
Z Jicai, Y Zongtao, L Jun, L Haiping… - … in cooperation with …, 2006 - Wiley Online Library
High rate of chronic hepatitis B virus (HBV) infection and p16 promoter methylation were
found in the majority of hepatocellular carcinoma (HCC). To investigate the potential linkage …
found in the majority of hepatocellular carcinoma (HCC). To investigate the potential linkage …
Promoter hypermethylation of p14 ARF , RB, and INK4 gene family in hepatocellular carcinoma with hepatitis B virus infection
JC Zhang, B Gao, ZT Yu, XB Liu, J Lu, F Xie, HJ Luo… - Tumor Biology, 2014 - Springer
Both hepatitis B virus (HBV) and gene methylation play important roles in
hepatocarcinogenesis. However, their association between HBV infection and gene …
hepatocarcinogenesis. However, their association between HBV infection and gene …
[HTML][HTML] Autoantibodies in Chinese patients with chronic hepatitis B: prevalence and clinical associations
BA Li, J Liu, J Hou, J Tang, J Zhang, J Xu… - World Journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To investigate the prevalence of autoantibodies and their associations with clinical
features in Chinese patients with chronic hepatitis B (CHB). METHODS: A total of 325 …
features in Chinese patients with chronic hepatitis B (CHB). METHODS: A total of 325 …