Gut microbial molecules in behavioural and neurodegenerative conditions

BD Needham, R Kaddurah-Daouk… - Nature Reviews …, 2020 - nature.com
Mounting evidence suggests that the gut microbiome impacts brain development and
function. Gut–brain connections may be mediated by an assortment of microbial molecules …

[HTML][HTML] Interplay of gut microbiota and oxidative stress: Perspective on neurodegeneration and neuroprotection

S Shandilya, S Kumar, NK Jha, KK Kesari… - Journal of Advanced …, 2022 - Elsevier
Background Recent research on the implications of gut microbiota on brain functions has
helped to gather important information on the relationship between them. Pathogenesis of …

New Insights Into the Mechanisms and Biological Roles of D-Amino Acids in Complex Eco-Systems

A Aliashkevich, L Alvarez, F Cava - Frontiers in microbiology, 2018 - frontiersin.org
In the environment bacteria share their habitat with a great diversity of organisms, from
microbes to humans, animals and plants. In these complex communities, the production of …

Control and dysregulation of redox signalling in the gastrointestinal tract

EL Campbell, SP Colgan - Nature Reviews Gastroenterology & …, 2019 - nature.com
Redox signalling in the gastrointestinal mucosa is held in an intricate balance. Potent
microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to …

d-amino Acids in Health and Disease: A Focus on Cancer

JJAJ Bastings, HM van Eijk, SW Olde Damink… - Nutrients, 2019 - mdpi.com
d-amino acids, the enantiomeric counterparts of l-amino acids, were long considered to be
non-functional or not even present in living organisms. Nowadays, d-amino acids are …

The peroxisome: an up-and-coming organelle in immunometabolism

F Di Cara, S Savary, WJ Kovacs, P Kim… - Trends in Cell …, 2023 - cell.com
Peroxisomes are essential metabolic organelles, well known for their roles in the
metabolism of complex lipids and reactive ionic species. In the past 10 years, peroxisomes …

Effects of metabolites derived from gut microbiota and hosts on pathogens

Z Li, G Quan, X Jiang, Y Yang, X Ding… - Frontiers in cellular …, 2018 - frontiersin.org
Intestinal metabolites participate in various physiological processes, including energy
metabolism, cell-to-cell communication, and host immunity. These metabolites mainly …

[HTML][HTML] Gut microbiota–derived D-serine protects against acute kidney injury

Y Nakade, Y Iwata, K Furuichi, M Mita, K Hamase… - JCI insight, 2018 - ncbi.nlm.nih.gov
Gut microbiota–derived metabolites play important roles in health and disease. D–amino
acids and their L-forms are metabolites of gut microbiota with distinct functions. In this study …

Promising application of D-amino acids toward clinical therapy

Y Shi, Z Hussain, Y Zhao - International journal of molecular sciences, 2022 - mdpi.com
The versatile roles of D-amino acids (D-AAs) in foods, diseases, and organisms, etc., have
been widely reported. They have been regarded, not only as biomarkers of diseases but …

Functional transcriptomics in diverse intestinal epithelial cell types reveals robust microRNA sensitivity in intestinal stem cells to microbial status

BCE Peck, AT Mah, WA Pitman, S Ding… - Journal of Biological …, 2017 - ASBMB
Gut microbiota play an important role in regulating the development of the host immune
system, metabolic rate, and at times, disease pathogenesis. The factors and mechanisms …