Lipid metabolism in critical illness

P Green, M Theilla, P Singer - Current Opinion in Clinical Nutrition …, 2016 - journals.lww.com
Lipid profile results are too often neglected by the clinician despite increasing knowledge in
the modifications related to septic state as well as the importance of these values in the …

Phytosterols, lipid administration, and liver disease during parenteral nutrition

GP Zaloga - Journal of Parenteral and Enteral Nutrition, 2015 - Wiley Online Library
Phytosterols are plant‐derived sterols that are structurally and functionally analogous to
cholesterol in vertebrate animals. Phytosterols are found in many foods and are part of the …

Pediatric parenteral nutrition-associated liver disease and cholestasis: Novel advances in pathomechanisms-based prevention and treatment

G Orso, C Mandato, C Veropalumbo, N Cecchi… - Digestive and Liver …, 2016 - Elsevier
Parenteral nutrition constitutes a life-saving therapeutic tool in patients unable to
ingest/absorb oral or enteral delivered nutrients. Liver function tests abnormalities are a …

Recurrence of hepatic encephalopathy after TIPS: effective prophylaxis with combination of lactulose and rifaximin

LL Seifert, P Schindler, M Schoster, JF Weller… - Journal of Clinical …, 2021 - mdpi.com
Background: Transjugular intrahepatic portosystemic shunt (TIPS) implantation is an
established procedure to treat portal hypertension with hepatic encephalopathy (HE) as a …

Down regulation of NDUFS1 is involved in the progression of parenteral-nutrition-associated liver disease by increasing oxidative stress

S Wan, G Maitiabula, P Wang, Y Zhang, X Gao… - The Journal of …, 2023 - Elsevier
Parenteral nutrition (PN)-associated liver disease (PNALD) is a common and life-threatening
complication of patients receiving PN. However, its definitive pathology remains unclear …

Novel strategies to prevent total parenteral nutrition‐induced gut and liver inflammation, and adverse metabolic outcomes

E Lucchinetti, PH Lou, P Wawrzyniak… - Molecular nutrition & …, 2021 - Wiley Online Library
Total parenteral nutrition (TPN) is a life‐saving therapy administered to millions of patients.
However, it is associated with significant adverse effects, namely liver injury, risk of …

Hepatoprotective and Antioxidant Activities of Oil from Baru Almonds (Dipteryx alata Vog.) in a Preclinical Model of Lipotoxicity and Dyslipidemia

MÁ Reis, RD Novaes, SR Baggio… - Evidence‐Based …, 2018 - Wiley Online Library
The oil obtained from baru (Dipteryx alata Vog.) almonds exhibits high energy value and is
reported in popular medicine for the treatment of rheumatic diseases and reproductive …

N-3 polyunsaturated fatty acids ameliorate hepatic steatosis via the PPAR-α/CPT-1α pathway in a mouse model of parenteral nutrition

F Tian, J Wang, H Sun, J Yang, P Wang, S Wan… - Biochemical and …, 2018 - Elsevier
Parenteral nutrition (PN) is one of the basic therapies for patients with intestinal failure;
however, hepatic steatosis associated with PN limits the long-term use of PN. N-3 …

Potential for omega-3 fatty acids to protect against the adverse effect of phytosterols: comparing laboratory outcomes in adult patients on home parenteral nutrition …

S Osowska, M Kunecki, J Sobocki, J Tokarczyk… - Biology, 2022 - mdpi.com
Simple Summary The choice of lipid emulsions (LEs) used in parenteral nutrition (PN) is
based on fatty acid composition and phytosterol content. Phytosterols are believed to be …

Alpha linolenic acid in maternal diet halts the lipid disarray due to saturated fatty acids in the liver of mice offspring at weaning

L Shomonov-Wagner, A Raz… - Lipids in health and …, 2015 - Springer
Background Alpha linolenic acid (ALA, 18: 3) in maternal diets has been shown to attenuate
obesity associated insulin resistance (IR) in adult offspring in mice. The objective in the …