Infections are estimated to contribute to 20% of all human tumours. These are mainly caused
by viruses, which explains why a direct bacterial contribution to cancer formation has been …

Legionella pneumophila and Coxiella burnetii are two evolutionarily related intracellular
pathogens that use the Dot/Icm type IV secretion system to translocate effectors into host …

Signalling by ubiquitination regulates virtually every cellular process in eukaryotes. Covalent
attachment of ubiquitin to a substrate is catalysed by the E1, E2 and E3 three-enzyme …

Phagocytosis and autophagy are two ancient, highly conserved processes involved,
respectively, in the removal of extracellular organisms and the destruction of organisms in …

Bacteria of the genus Legionella are natural pathogens of amoebae that can cause a severe
pneumonia in humans called Legionnaires' Disease. Human disease results from inhalation …

The genus Legionella contains more than 50 species, of which at least 24 have been
associated with human infection. The best-characterized member of the genus, Legionella …

The pathogenesis of Legionella pneumophila is derived from its growth within lung
macrophages after aerosols are inhaled from contaminated water sources. Interest in this …

Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

The intracellular pathogen Brucella is the causative agent of brucellosis, a worldwide
zoonosis that affects mammals, including humans. Essential to Brucella virulence is its …

Macrophages and protozoa ingest bacteria by phagocytosis and destroy these microbes
using a conserved pathway that mediates fusion of the phagosome with lysosomes. To …