Metformin: a review of characteristics, properties, analytical methods and impact in the green chemistry

MT da Trindade, AC Kogawa… - Critical reviews in …, 2018 - Taylor & Francis
Diabetes mellitus (DM) is considered a public health problem. The initial treatment consists
of improving the lifestyle and making changes in the diet. When these changes are not …

UPLC simultaneous determination of empagliflozin, linagliptin and metformin

BM Ayoub - RSC advances, 2015 - pubs.rsc.org
The first UPLC method for simultaneous determination of empagliflozin, linagliptin and
metformin hydrochloride in the different combinations of their pharmaceutical dosage forms …

Deduction of the operable design space of RP-HPLC technique for the simultaneous estimation of metformin, pioglitazone, and glimepiride

AA Marie, SF Hammad, MM Salim, MM Elkhodary… - Scientific reports, 2023 - nature.com
Abstract A reversed-phase RP-HPLC method was developed for the simultaneous
determination of metformin hydrochloride (MET), pioglitazone (PIO), and glimepiride (GLM) …

Investigating the role of the reduced solubility of the pirfenidone–fumaric acid cocrystal in sustaining the release rate from its tablet dosage form by conducting …

N Kumari, P Roy, S Roy, PK Parmar… - Molecular …, 2022 - ACS Publications
Pirfenidone (PFD) is the first pharmacological agent approved by the US Food and Drug
Administration (FDA) in 2014 for the treatment of idiopathic pulmonary fibrosis (IPF). The …

Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm

K Chaudhari, J Wang, Y Xu, A Winters, L Wang… - PLoS …, 2020 - journals.plos.org
Metformin, an anti-diabetes drug, has been recently emerging as a potential “anti-aging”
intervention based on its reported beneficial actions against aging in preclinical studies …

[HTML][HTML] Simultaneous determination of atorvastatin, metformin and glimepiride in human plasma by LC–MS/MS and its application to a human pharmacokinetic study

SR Polagani, NR Pilli, R Gajula, V Gandu - Journal of Pharmaceutical …, 2013 - Elsevier
A simple, rapid and sensitive liquid chromatography-tandem mass spectrometric (LC–
MS/MS) assay method has been developed and fully validated for the simultaneous …

A systematic and critical review on bioanalytical method validation using the example of simultaneous quantitation of antidiabetic agents in blood

MM Fachi, LP Leonart, LB Cerqueira… - … of Chromatography B, 2017 - Elsevier
A systematic and critical review was conducted on bioanalytical methods validated to
quantify combinations of antidiabetic agents in human blood. The aim of this article was to …

Ultrahigh-throughput and chromatography-free bioanalysis of polar analytes with acoustic ejection mass spectrometry

A Wagner, J Zhang, C Liu, TR Covey, TV Olah… - Analytical …, 2020 - ACS Publications
Bioanalysis of polar analytes using liquid chromatography–tandem mass spectrometry (LC-
MS/MS) remains a significant challenge because of their poor chromatographic retention on …

[HTML][HTML] Spectroflourometric and spectrophotometric methods for the determination of sitagliptin in binary mixture with metformin and ternary mixture with metformin …

RI El-Bagary, EF Elkady, BM Ayoub - International journal of …, 2011 - ncbi.nlm.nih.gov
Simple, accurate and precise spectroflourometric and spectrophotometric methods have
been developed and validated for the determination of sitagliptin phosphate monohydrate …

Molecularly imprinted potentiometric sensor for nanomolar determination of pioglitazone hydrochloride in pharmaceutical formulations

MM El‐Beshlawy, FM Abdel‐Haleem… - …, 2021 - Wiley Online Library
Pioglitazone Hydrochloride (PG) is an insulin‐sensitizing drug and is indicated for the
treatment of type II diabetes. In this study, newly molecularly imprinted electrochemical …