HIV/AIDS epidemiology, pathogenesis, prevention, and treatment

V Simon, DD Ho, QA Karim - The Lancet, 2006 - thelancet.com
The HIV-1 pandemic is a complex mix of diverse epidemics within and between countries
and regions of the world, and is undoubtedly the defining public-health crisis of our time …

Nano/Microfluidics for diagnosis of infectious diseases in developing countries

WG Lee, YG Kim, BG Chung, U Demirci… - Advanced drug delivery …, 2010 - Elsevier
Nano/Microfluidic technologies are emerging as powerful enabling tools for diagnosis and
monitoring of infectious diseases in both developed and developing countries. Miniaturized …

Integrating microfluidics and lensless imaging for point-of-care testing

SJ Moon, HO Keles, A Ozcan… - Biosensors and …, 2009 - Elsevier
We demonstrate an integrated platform that merges a microfluidic chip with lensless imaging
to target CD4+ T-lymphocyte counts for HIV point-of-care testing at resource-limited settings …

Micro-a-fluidics ELISA for rapid CD4 cell count at the point-of-care

SQ Wang, S Tasoglu, PZ Chen, M Chen, R Akbas… - Scientific reports, 2014 - nature.com
HIV has become one of the most devastating pathogens in human history. Despite fast
progress in HIV-related basic research, antiretroviral therapy (ART) remains the most …

CD4 immunophenotyping in HIV infection

D Barnett, B Walker, A Landay, TN Denny - Nature Reviews …, 2008 - nature.com
The ability to rapidly identify immune cell subsets such as CD4 cells, which became possible
around the same time as the onset of the HIV/AIDS pandemic, was one of the greatest …

Enumeration of CD4+ T-Cells Using a Portable Microchip Count Platform in Tanzanian HIV-Infected Patients

SJ Moon, UA Gurkan, J Blander, WW Fawzi, S Aboud… - PloS one, 2011 - journals.plos.org
Background CD4+ T-lymphocyte count (CD4 count) is a standard method used to monitor
HIV-infected patients during anti-retroviral therapy (ART). The World Health Organization …

Multisite evaluation of a point-of-care instrument for CD4+ T-cell enumeration using venous and finger-prick blood: the PIMA CD4

PA Diaw, G Daneau, AA Coly, BP Ndiaye… - JAIDS Journal of …, 2011 - journals.lww.com
Background CD4+ T-cell enumeration (CD4 count) is used as a criterion to initiate
antiretroviral therapy (ART) in HIV patients and to monitor treatment efficacy. However …

Large‐scale affordable Panleucogated CD4+ testing with proactive internal and external quality assessment: In support of the South African national comprehensive …

DK Glencross, G Janossy, LM Coetzee… - Cytometry Part B …, 2008 - Wiley Online Library
Background: In order to expand the treatment of human immunodeficiency virus‐1 (HIV)
infected patients in Africa, millions will require cost‐effective CD4 counts. Supporting …

Role of microfluidics-based point-of-care testing (POCT) for clinical applications

A Parihar, DS Parihar, P Ranjan… - … Microfluidics Based Point …, 2022 - taylorfrancis.com
The fast and timely detection of various infectious and other diseases is a critical step in
deciding therapeutic outcomes which in turn enhance patient health and survival rates. In …

African regional external quality assessment for CD4 T‐cell enumeration: development, outcomes, and performance of laboratories

DK Glencross, HM Aggett, WS Stevens… - Cytometry Part B …, 2008 - Wiley Online Library
Abstract Background: An independent African Regional External Quality Assessment
Scheme (AFREQAS) was implemented from Johannesburg. The aim was to establish a …