[HTML][HTML] An updated review on synthetic cathinones
J Soares, VM Costa, ML Bastos, F Carvalho… - Archives of …, 2021 - Springer
Cathinone, the main psychoactive compound found in the plant Catha edulis Forsk.(khat), is
a β-keto analogue of amphetamine, sharing not only the phenethylamine structure, but also …
a β-keto analogue of amphetamine, sharing not only the phenethylamine structure, but also …
Structure–Activity Relationship of Synthetic Cathinones: An Updated Review
The escalating prevalence of new psychoactive substances (NPSs) poses a significant
public health challenge, evidenced by the vast chemical diversity, with over 500 substances …
public health challenge, evidenced by the vast chemical diversity, with over 500 substances …
Synthetic cathinones induce cell death in dopaminergic SH-SY5Y cells via stimulating mitochondrial dysfunction
HS Leong, M Philp, M Simone, PK Witting… - International journal of …, 2020 - mdpi.com
Increasing reports of neurological and psychiatric complications due to psychostimulant
synthetic cathinones (SCs) have recently raised public concern. However, the precise …
synthetic cathinones (SCs) have recently raised public concern. However, the precise …
Novel psychoactive substances: the razor's edge between therapeutical potential and psychoactive recreational misuse
B Correia, J Fernandes, MJ Botica, C Ferreira… - Medicines, 2022 - mdpi.com
Background: Novel psychoactive substances (NPS) are compounds of natural and synthetic
origin, similar to traditional drugs of abuse. NPS are involved in a contemporary trend whose …
origin, similar to traditional drugs of abuse. NPS are involved in a contemporary trend whose …
Determination of selected cathinones in blood by solid-phase extraction and GC–MS
M Antunes, M Sequeira… - Journal of Analytical …, 2021 - academic.oup.com
The emergence of potentially dangerous new psychoactive substances (NPS) is challenging
for forensic laboratories, as well as the ability to develop and validate methods for a rapid …
for forensic laboratories, as well as the ability to develop and validate methods for a rapid …
Quantitative spectrofluorometric assay detecting nuclear condensation and fragmentation in intact cells
At present, nuclear condensation and fragmentation have been estimated also using
Hoechst probes in fluorescence microscopy and flow cytometry. However, none of the …
Hoechst probes in fluorescence microscopy and flow cytometry. However, none of the …
Semi-Preparative Separation, Absolute Configuration, Stereochemical Stability and Effects on Human Neuronal Cells of MDPV Enantiomers
AS Almeida, B Silva, JP Silva, JA Pereira, F Remião… - Molecules, 2023 - mdpi.com
Synthetic cathinones, such as 3, 4-methylenedioxypyrovalerone (MDPV), are widely abused
due to their psychostimulant effects. As they are chiral molecules, studies of their …
due to their psychostimulant effects. As they are chiral molecules, studies of their …
Four synthetic cathinones: 3-chloromethcathinone, 4-chloromethcathinone, 4-fluoro-α-pyrrolidinopentiophenone, and 4-methoxy-α-pyrrolidinopentiophenone produce …
J Wojcieszak, K Kuczyńska, JB Zawilska - Neurotoxicity Research, 2020 - Springer
Abstract Two chloromethcathinones, 3-chloromethcathinone (3-CMC) and 4-
chloromethcathinone (4-CMC), and two para-substituted α-pyrrolidinophenones, 4-methoxy …
chloromethcathinone (4-CMC), and two para-substituted α-pyrrolidinophenones, 4-methoxy …
4-Isobutylmethcathinone—A Novel Synthetic Cathinone with High In Vitro Cytotoxicity and Strong Receptor Binding Preference of Enantiomers
M Paškan, S Rimpelová, V Svobodová Pavlíčková… - Pharmaceuticals, 2022 - mdpi.com
New psychoactive substances and among them synthetic cathinones represent a significant
threat to human health globally. However, within such a large pool of substances derived …
threat to human health globally. However, within such a large pool of substances derived …
[HTML][HTML] Synthesis of emerging cathinones and validation of a SPE GC–MS method for their simultaneous quantification in blood
S Júlio, RA Ferro, S Santos, A Alexandre… - Analytical and …, 2023 - Springer
Over the past 15 years, synthetic cathinones have emerged as an important class of new
psychoactive substances (NPS) worldwide. The proliferation of these psychostimulants and …
psychoactive substances (NPS) worldwide. The proliferation of these psychostimulants and …