Technological innovations in photochemistry for organic synthesis: flow chemistry, high-throughput experimentation, scale-up, and photoelectrochemistry

L Buglioni, F Raymenants, A Slattery… - Chemical …, 2021 - ACS Publications
Photoinduced chemical transformations have received in recent years a tremendous amount
of attention, providing a plethora of opportunities to synthetic organic chemists. However …

Photocatalysis in the life science industry

L Candish, KD Collins, GC Cook, JJ Douglas… - Chemical …, 2021 - ACS Publications
In the pursuit of new pharmaceuticals and agrochemicals, chemists in the life science
industry require access to mild and robust synthetic methodologies to systematically modify …

[HTML][HTML] Recent advances in visible light-activated radical coupling reactions triggered by (i) ruthenium,(ii) iridium and (iii) organic photoredox agents

JD Bell, JA Murphy - Chemical Society Reviews, 2021 - pubs.rsc.org
Photoredox chemistry with organic or transition metal agents has been reviewed in earlier
years, but such is the pace of progress that we will overlap very little with earlier …

Generation of alkyl radicals: from the tyranny of tin to the photon democracy

S Crespi, M Fagnoni - Chemical reviews, 2020 - ACS Publications
Alkyl radicals are key intermediates in organic synthesis. Their classic generation from alkyl
halides has a severe drawback due to the employment of toxic tin hydrides to the point that …

Synthetic photoelectrochemistry

JP Barham, B König - Angewandte Chemie International …, 2020 - Wiley Online Library
Photoredox catalysis (PRC) and synthetic organic electrochemistry (SOE) are often
considered competing technologies in organic synthesis. Their fusion has been largely …

Scalability of photochemical reactions in continuous flow mode

K Donnelly, M Baumann - Journal of Flow Chemistry, 2021 - Springer
Continuous flow photochemistry as a field has witnessed an increasing popularity over the
last decade in both academia and industry. Key drivers for this development are safety …

Programmable late-stage functionalization of bridge-substituted bicyclo [1.1. 1] pentane bis-boronates

Y Yang, J Tsien, R Dykstra, SJ Chen, JB Wang… - Nature …, 2024 - nature.com
Modular functionalization enables versatile exploration of chemical space and has been
broadly applied in structure–activity relationship (SAR) studies of aromatic scaffolds during …

Boron, silicon, nitrogen and sulfur-based contemporary precursors for the generation of alkyl radicals by single electron transfer and their synthetic utilization

V Corcé, C Ollivier, L Fensterbank - Chemical Society Reviews, 2022 - pubs.rsc.org
Recent developments in the use of boron, silicon, nitrogen and sulfur derivatives in single-
electron transfer reactions for the generation of alkyl radicals are described. Photoredox …

The impact of boron hybridisation on photocatalytic processes

A Marotta, CE Adams, JJ Molloy - Angewandte Chemie, 2022 - Wiley Online Library
Recently the fruitful merger of organoboron chemistry and photocatalysis has come to the
forefront of organic synthesis, resulting in the development of new technologies to access …

Rapid optimization of photoredox reactions for continuous-flow systems using microscale batch technology

M González-Esguevillas, DF Fernández… - ACS Central …, 2021 - ACS Publications
Photoredox catalysis has emerged as a powerful and versatile platform for the synthesis of
complex molecules. While photocatalysis is already broadly used in small-scale batch …