Current and future treatment strategies for rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, and can be
subcategorized histologically and/or based on PAX-FOXO1 fusion gene status. Over the last …
subcategorized histologically and/or based on PAX-FOXO1 fusion gene status. Over the last …
Common musculoskeletal tumors of childhood and adolescence
CAS Arndt, PS Rose, AL Folpe, NN Laack - Mayo Clinic Proceedings, 2012 - Elsevier
Osteosarcoma, Ewing sarcoma, and rhabdomyosarcoma are the most common malignant
musculoskeletal tumors in children and adolescents. Today, most patients can be cured …
musculoskeletal tumors in children and adolescents. Today, most patients can be cured …
A Molecular Study of Pediatric Spindle and Sclerosing Rhabdomyosarcoma: Identification of Novel and Recurrent: VGLL2-: related Fusions in Infantile Cases
Sclerosing rhabdomyosarcoma (ScRMS) and spindle cell rhabdomyosarcoma (SRMS) have
been recently reclassified as a stand-alone pathologic entity, separate from embryonal RMS …
been recently reclassified as a stand-alone pathologic entity, separate from embryonal RMS …
Prognostic factors in metastatic rhabdomyosarcomas: results of a pooled analysis from United States and European cooperative groups
O Oberlin, A Rey, E Lyden, G Bisogno… - Journal of Clinical …, 2008 - ascopubs.org
Purpose To identify risk factors associated with outcome in children with metastatic
rhabdomyosarcoma in a large cohort of patients Patients and Methods Pooled data were …
rhabdomyosarcoma in a large cohort of patients Patients and Methods Pooled data were …
Randomized phase II trial of bevacizumab or temsirolimus in combination with chemotherapy for first relapse rhabdomyosarcoma: a report from the Children's …
L Mascarenhas, YY Chi, P Hingorani… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE The primary aim of this clinical trial was to prioritize bevacizumab or temsirolimus
for additional investigation in rhabdomyosarcoma (RMS) when administered in combination …
for additional investigation in rhabdomyosarcoma (RMS) when administered in combination …
Metastatic Rhabdomyosarcoma: Results of the European Paediatric Soft Tissue Sarcoma Study Group MTS 2008 Study and Pooled Analysis With the Concurrent …
RA Schoot, JC Chisholm, M Casanova… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Outcome for patients with metastatic rhabdomyosarcoma (RMS) is poor. This
study presents the results of the MTS 2008 study with a pooled analysis including patients …
study presents the results of the MTS 2008 study with a pooled analysis including patients …
Adjuvant immunotherapy to improve outcome in high-risk pediatric sarcomas
MS Merchant, D Bernstein, M Amoako, K Baird… - Clinical Cancer …, 2016 - AACR
Purpose: Patients with metastatic or relapsed pediatric sarcomas receive cytotoxic regimens
that induce high remission rates associated with profound lymphocyte depletion, but …
that induce high remission rates associated with profound lymphocyte depletion, but …
Histologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology …
AR Weiss, ER Lyden, JR Anderson… - Journal of clinical …, 2013 - ascopubs.org
Purpose To simplify the recommended staging evaluation by correlating tumor and clinical
features with patterns of distant metastasis in newly diagnosed patients with embryonal …
features with patterns of distant metastasis in newly diagnosed patients with embryonal …
Recent advances and challenges in the treatment of rhabdomyosarcoma
Rhabdomyosarcoma, the most common soft tissue sarcoma noted in childhood, requires
multimodality treatment, including chemotherapy, surgical resection, and/or radiation …
multimodality treatment, including chemotherapy, surgical resection, and/or radiation …
Anaplastic lymphoma kinase aberrations in rhabdomyosarcoma: clinical and prognostic implications
JC van Gaal, UE Flucke, MHS Roeffen… - Journal of clinical …, 2012 - ascopubs.org
Purpose The aim of this study is to investigate anaplastic lymphoma kinase (ALK) protein
expression and underlying genetic aberrations in rhabdomyosarcoma (RMS), with special …
expression and underlying genetic aberrations in rhabdomyosarcoma (RMS), with special …