Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort …

D Hillus, T Schwarz, P Tober-Lau… - The Lancet …, 2021 - thelancet.com
Background Heterologous vaccine regimens have been widely discussed as a way to
mitigate intermittent supply shortages and to improve immunogenicity and safety of COVID …

Remdesivir for the treatment of COVID‐19

Cochrane Haematology Group… - Cochrane Database …, 1996 - cochranelibrary.com
Background Remdesivir is an antiviral medicine approved for the treatment of mild‐to‐
moderate coronavirus disease 2019 (COVID‐19). This led to widespread implementation …

ImmunosuppressiveTherapies differently modulate Humoral-and T-cell-specific responses to COVID-19 mRNA vaccine in rheumatoid arthritis patients

A Picchianti-Diamanti, A Aiello, B Laganà… - Frontiers in …, 2021 - frontiersin.org
Objective To assess in rheumatoid arthritis (RA) patients, treated with different
immunosuppressive therapies, the induction of SARS-CoV-2-specific immune response …

Long-term immunogenicity of BNT162b2 vaccination in older people and younger health-care workers

P Tober-Lau, T Schwarz, K Vanshylla… - The Lancet …, 2021 - thelancet.com
Health-care workers were enrolled at Charité-Universitätsmedizin Berlin (n= 107) and older
people were enrolled at an assisted living facility in Berlin, Germany (n= 82).(A) Anti-S1 IgG …

Impaired functional T-cell response to SARS-CoV-2 after two doses of BNT162b2 mRNA vaccine in older people

J Demaret, B Corroyer-Simovic, EK Alidjinou… - Frontiers in …, 2021 - frontiersin.org
Long-term care facility (LTCF) older residents display physiological alterations of cellular
and humoral immunity that affect vaccine responses. Preliminary reports suggested a low …

High avidity of vaccine-induced immunoglobulin G against SARS-CoV-2: potential relevance for protective humoral immunity

G Bauer - Exploration of Immunology, 2022 - explorationpub.com
Avidity of immunoglobulin G (IgG) is defined as its binding strength to its target antigen. As a
consequence of affinity maturation of the IgG response, avidity is maturing as well …

B and T cell responses after a third dose of SARS-CoV-2 vaccine in kidney transplant recipients

E Schrezenmeier, H Rincon-Arevalo… - Journal of the …, 2021 - journals.lww.com
Background Accumulating evidence sugges ts solid organ transplant recipients, as opposed
to the general population, show strongly impaired responsiveness toward standard SARS …

Vaccine-induced correlate of protection against fatal COVID-19 in older and frail adults during waves of neutralization-resistant variants of concern: an observational …

L Vikström, P Fjällström, YD Gwon… - The Lancet Regional …, 2023 - thelancet.com
Background To inform future preventive measures including repeated vaccinations, we have
searched for a clinically useful immune correlate of protection against fatal COVID-19 …

Type of vaccine and immunosuppressive therapy but not diagnosis critically influence antibody response after COVID-19 vaccination in patients with rheumatic …

LM Frommert, ANA de Silva, J Zernicke, V Scholz… - RMD open, 2022 - rmdopen.bmj.com
Objective The development of sufficient COVID-19 vaccines has been a big breakthrough in
fighting the global SARS-CoV-2 pandemic. However, vaccination effectiveness can be …

Differences in SARS-CoV-2 specific humoral and cellular immune responses after contralateral and ipsilateral COVID-19 vaccination

L Ziegler, V Klemis, T Schmidt, S Schneitler, C Baum… - …, 2023 - thelancet.com
Background Individual doses of dual-dose vaccine-regimens are sequentially administered
into the deltoid muscle, but little attention has so far been paid to the immunological effects …