Clostridioides difficile is the most common cause of nosocomial antibiotic-associated
diarrhea, and is responsible for a spectrum of diseases characterized by high levels of …

Clostridium difficile infection (CDI) is the leading cause of antimicrobial and health care-
associated diarrhea in humans, presenting a significant burden to global health care …

Recombination is an important evolutionary force in bacteria, but it remains challenging to
reconstruct the imports that occurred in the ancestry of a genomic sample. Here we present …

Summary Background The control of Clostridium difficile infections is an international clinical
challenge. The incidence of C difficile in England declined by roughly 80% after 2006 …

The outer surface of many archaea and bacteria is coated with a proteinaceous surface
layer (known as an S-layer), which is formed by the self-assembly of monomeric proteins …

Many bacteria and archaea possess a two-dimensional protein array, or S-layer, that covers
the cell surface and plays crucial roles in cell physiology. Here, we report the crystal …

The worldwide emergence of epidemic strains of Clostridium difficile linked to increased
disease severity and mortality has resulted in greater research efforts toward determining …

Clostridium difficile PCR ribotype (RT) 014 is well-established in both human and porcine
populations in Australia, raising the possibility that C. difficile infection (CDI) may have a …

Clostridium difficile is a major nosocomial pathogen and the main causative agent of
antibiotic-associated diarrhoea. The organism produces two potent toxins, A and B, which …

Clostridium difficile is the prominent etiological agent of healthcare-associated diarrhea. The
disease symptoms range from mild diarrhea to life-threatening pseudomembranous colitis …