Optic neuritis is an inflammatory optic neuropathy that affects many patients with multiple
sclerosis (MS) at some point during their disease course. Differentiation of acute episodes of …

Background Structural retinal imaging biomarkers are important for early recognition and
monitoring of inflammation and neurodegeneration in multiple sclerosis. With the …

Objective The aim of this work was to determine whether atrophy of specific retinal layers
and brain substructures are associated over time, in order to further validate the utility of …

Importance Retinal structures may serve as a biomarker for dementia, but longitudinal
studies examining this link are lacking. Objective To investigate the association of inner …

Background Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been
reported in patients with aquaporin-4 antibody (AQP4-IgG)-negative neuromyelitis optica …

Importance Identifing potential screening tests for future cognitive decline is a priority for
developing treatments for and the prevention of dementia. Objective To examine the …

Background and Objectives Relapsing-remitting multiple sclerosis (RRMS), aquaporin-4
antibody–positive neuromyelitis optica spectrum disorder (AQP4-NMOSD), and myelin …

Background: Retinal optical coherence tomography (OCT) permits quantification of retinal
layer atrophy relevant to assessment of neurodegeneration in multiple sclerosis (MS) …

Background and objectives Recent literature on multiple sclerosis (MS) demonstrates the
growing implementation of optical coherence tomography–angiography (OCT-A) to discover …

Objective To evaluate changes over 3 years in the thickness of inner retinal layers including
the peripapillary retinal nerve fiber layer (pRNFL), and combined macular ganglion cell and …