Prefrontal cortex and social cognition in mouse and man
LK Bicks, H Koike, S Akbarian, H Morishita - Frontiers in psychology, 2015 - frontiersin.org
Social cognition is a complex process that requires the integration of a wide variety of
behaviors, including salience, reward-seeking, motivation, knowledge of self and others …
behaviors, including salience, reward-seeking, motivation, knowledge of self and others …
The space where aging acts: Focus on the GABA ergic synapse
A Rozycka, M Liguz‐Lecznar - Aging cell, 2017 - Wiley Online Library
As it was established that aging is not associated with massive neuronal loss, as was
believed in the mid‐20th Century, scientific interest has addressed the influence of aging on …
believed in the mid‐20th Century, scientific interest has addressed the influence of aging on …
[HTML][HTML] Human iPSC glial mouse chimeras reveal glial contributions to schizophrenia
In this study, we investigated whether intrinsic glial dysfunction contributes to the
pathogenesis of schizophrenia (SCZ). Our approach was to establish humanized glial …
pathogenesis of schizophrenia (SCZ). Our approach was to establish humanized glial …
[HTML][HTML] Genetics of autism spectrum disorder: current status and possible clinical applications
H Yoo - Experimental neurobiology, 2015 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is one of the most complex behavioral disorders with a
strong genetic influence. The objectives of this article are to review the current status of …
strong genetic influence. The objectives of this article are to review the current status of …
Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder
Abstract Neuroligin-4 (NLGN4) loss-of-function mutations are associated with monogenic
heritable autism spectrum disorder (ASD) and cause alterations in both synaptic and …
heritable autism spectrum disorder (ASD) and cause alterations in both synaptic and …
HS, an ancient molecular recognition and information storage glycosaminoglycan, equips hs-proteoglycans with diverse matrix and cell-interactive properties …
Heparan sulfate is a ubiquitous, variably sulfated interactive glycosaminoglycan that
consists of repeating disaccharides of glucuronic acid and glucosamine that are subject to a …
consists of repeating disaccharides of glucuronic acid and glucosamine that are subject to a …
Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine
Human postmortem studies suggest a major role for abnormalities in GABAergic
interneurons in the prefrontal cortex in schizophrenia. Cortical interneurons differentiated …
interneurons in the prefrontal cortex in schizophrenia. Cortical interneurons differentiated …
Neural tissue homeostasis and repair is regulated via CS and DS proteoglycan motifs
Chondroitin sulfate (CS) is the most abundant and widely distributed glycosaminoglycan
(GAG) in the human body. As a component of proteoglycans (PGs) it has numerous roles in …
(GAG) in the human body. As a component of proteoglycans (PGs) it has numerous roles in …
Neurexin controls plasticity of a mature, sexually dimorphic neuron
During development and adulthood, brain plasticity is evident at several levels, from
synaptic structure and function to the outgrowth of dendrites and axons. Whether and how …
synaptic structure and function to the outgrowth of dendrites and axons. Whether and how …