Introduction• Free radical scavenging‐Scavenging superoxide and other ROS‐Scavenging
hydroxyl radical and other ROS‐Stable radical scavenging• Metal ion (Fe2+, Fe3+, Cu2+ …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Peroxynitrite—the product of the diffusion-controlled reaction of nitric oxide with superoxide
radical—is a short-lived oxidant species that is a potent inducer of cell death. Conditions in …

Poly (ADP-ribose) polymerase-1 (PARP-1) is a member of the PARP enzyme family
consisting of PARP-1 and several recently identified novel poly (ADP-ribosylating) enzymes …

The rate of oxygen consumption by certain tissues is impaired when mice or rats are injected
with lipopolysaccharide. A similar change in the rate of oxygen consumption is observed …

Reactive oxygen species (ROS) mediate apoptosis in a number of cell types. We studied the
role that ROS play in activated T cell apoptosis by activating T cells in vivo and then culturing …

Mammalian poly (ADP-ribose) polymerase 1 (PARP-1) is an abundant nuclear chromatin-
associated protein and belongs to a large family of enzymes that catalyzes the transfer of …

Reactive oxygen species (ROS) have been implicated in a wide range of degenerative
processes including amyotrophic lateral sclerosis, ischemic heart disease, Alzheimer …

The free radical nitric oxide (NO) has emerged in recent years as a fundamental signaling
molecule for the maintenance of homeostasis, as well as a potent cytotoxic effector involved …

The most common cause of death in patients with sepsis is deterioration of the function of
multiple organs. This syndrome has been called the multiple organ dysfunction syndrome …