Benefiting from the impressive increase in fundamental knowledge, the last 20 years have
shown a continuous burst of new ideas and consequently a plethora of new catalytic …

The radical-involved 1, 2-difunctionalization of alkenes has developed into a robust tool for
preparation of complex organic molecules. Despite significant advances in this area, the …

Conspectus The direct transformation of C–H bonds into diverse functional groups
represents one of the most atom-and step-economical strategies for organic synthesis and …

Vicinal diamines are a common structural motif in bioactive natural products, therapeutic
agents, and molecular catalysts, motivating the continuing development of efficient …

This Perspective illustrates the defining characteristics of free radical chemistry, beginning
with its rich and storied history. Studies from our laboratory are discussed along with recent …

Given its many distinct characteristics, electrochemistry represents an attractive approach to
meet the prevailing trends in organic synthesis. In particular, electrocatalysis—a process that …

The construction of carbon–heteroatom bonds is one of the most active areas of research in
organic chemistry because the function of organic molecules is often derived from the …

Conspectus Asymmetric functionalization of alkyl radicals represents a robust yet
underdeveloped method for efficient construction and decoration of carbon skeletons in …

The C–O bond is ubiquitous in biologically active molecules, pharmaceutical agents, and
functional materials, thereby making it an important functional group. Consequently, the …

Kharasch–Sosnovsky reaction is one of the most powerful methods for allylic oxidation of
alkenes. However, the inherent radical mechanism and use of peroxides as both oxidants …