Background Tuberculosis (TB) which is caused by Mycobacterium tuberculosis poses a
significant public health global treat. Tuberculosis meningitis (TBM) accounts for …

TB affects around 10.6 million people each year and there are now around 155 million TB
survivors. TB and its treatments can lead to permanently impaired health and wellbeing. In …

Diagnosis of tuberculous meningitis (TBM) remains challenging due to a paucity of high-
performance diagnostics. Even those that have reasonable sensitivity are not adequate to …

Tuberculous meningitis (TBM) is the most lethal form of tuberculosis. The incidence and
mortality of TBM is unknown due to diagnostic challenges and limited disaggregated …

Background Few treatment options exist for patients with severe central nervous system
(CNS) tuberculosis (TB) worsening due to inflammatory lesions, despite optimal …

Background Little is known about the impact of drug-resistance on clinical outcomes among
patients with tuberculosis meningitis (TBM). Methods A retrospective cohort study among …

Adjunctive treatment with antiinflammatory corticosteroids like dexamethasone increases
survival in tuberculosis meningitis. Dexamethasone responsiveness associates with a C/T …

Background The purpose of this study was to assess if single nucleotide polymorphisms
(SNPs) in lung mucins MUC5B and MUC5AC are associated with Mycobacterium …

Abstract Background Cerebrospinal fluid (CSF) Ziehl–Neelsen acid-fast bacilli (AFB) smear
is a rapid, cheap, widely available test for tuberculous meningitis (TBM). Yet, reported test …

Background Tuberculous meningitis (TBM) is the most lethal form of tuberculosis worldwide.
Data on critically ill TBM patients in the intensive care unit (ICU) of China are lacking. We …