Sixty DNA trinucleotide cation radicals covering a large part of the genetic code alphabet
were generated by electron transfer in the gas phase, and their chemistry was studied by …

The catalytic strategies of small self-cleaving ribozymes often involve interactions between
nucleobases and the ribonucleic acid (RNA) backbone. Here we show that multiply …

Dissociations of DNA trinucleotide codons as gas-phase singly and doubly protonated ions
were studied by tandem mass spectrometry using 15N-labeling to resolve identity in the …

The molecular family of nucleotide triphosphates (NTPs), with adenosine 5′-triphosphate
(ATP) as its best-known member, is of high biochemical importance as their phosphodiester …

The chemical difference between DNA and RNA nucleosides is their 2′-hydrogen versus
2′-hydroxyl substituents. Modification of the ribosyl moiety at the 2′-position and 2′-O …

We have conducted here a theoretical exploration, discussing the distinct excited state
lifetimes reported experimentally for the two lowest lying protonated isomers of uracil. In this …

Fluorinated nucleosides are well-established as anticancer and antiviral medications. As
with many pharmaceuticals, the effects of fluorine modifications are often only partially …

Synergistic infrared multiple photon dissociation (IRMPD) action spectroscopy experiments
and electronic structure calculations revealed that both 2, 4-dihydroxy tautomers and O2 …

Long-range electron transfer in proteins can be rationalized as a sequential short-distance
electron-hopping processes via amino acid residues having low ionization energy as relay …

The 2′-substituents distinguish DNA from RNA nucleosides. 2′-O-methylation occurs
naturally in RNA and plays important roles in biological processes. Such 2′-modifications …