Reactive oxygen species and cell signaling. Review

D Averill-Bates - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2024 - Elsevier
Reactive oxygen species (ROS) is a term encompassing a group of highly reactive oxygen-
derived molecules. In physiological systems, ROS production exists in concert with …

The role of ROS in tumor infiltrating immune cells and cancer immunotherapy

R Shah, B Ibis, M Kashyap, VA Boussiotis - Metabolism, 2024 - Elsevier
Reactive oxygen species (ROS) are a group of short-lived highly reactive molecules formed
intracellularly from molecular oxygen. ROS can alter biochemical, transcriptional, and …

Dual-site fluorescent probe for visualizing the metabolism of Cys in living cells

Y Yue, F Huo, P Ning, Y Zhang, J Chao… - Journal of the …, 2017 - ACS Publications
Fluorescent probes, as noninvasive tools for visualizing the metabolism of biomolecules,
hold great potential to explore their physiological and pathological processes. For cysteine …

Oxidative stress, prooxidants, and antioxidants: the interplay

A Rahal, A Kumar, V Singh, B Yadav… - BioMed research …, 2014 - Wiley Online Library
Oxidative stress is a normal phenomenon in the body. Under normal conditions, the
physiologically important intracellular levels of reactive oxygen species (ROS) are …

[HTML][HTML] Physiological roles of mitochondrial reactive oxygen species

LA Sena, NS Chandel - Molecular cell, 2012 - cell.com
Historically, mitochondrial reactive oxygen species (mROS) were thought to exclusively
cause cellular damage and lack a physiological function. Accumulation of ROS and …

Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants

B Poljsak, D Šuput, I Milisav - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Free radical damage is linked to formation of many degenerative diseases, including cancer,
cardiovascular disease, cataracts, and aging. Excessive reactive oxygen species (ROS) …

Reactive oxygen species: involvement in T cell signaling and metabolism

DG Franchina, C Dostert, D Brenner - Trends in immunology, 2018 - cell.com
T cells are a central component of defenses against pathogens and tumors. Their effector
functions are sustained by specific metabolic changes that occur upon activation, and these …

Mitochondrial ROS regulation of proliferating cells

L Diebold, NS Chandel - Free Radical Biology and Medicine, 2016 - Elsevier
Once thought of exclusively as damaging molecules, reactive oxygen species (ROS) are
becoming increasingly appreciated for the role they play in cellular signaling through redox …

Drug resistance in glioblastoma: the two faces of oxidative stress

C Olivier, L Oliver, L Lalier, FM Vallette - Frontiers in molecular …, 2021 - frontiersin.org
Glioblastomas (GBM) are the most common primary brain tumor with a median survival of 15
months. A population of cells with stem cell properties (glioblastoma stem cells, GSCs) …

Mitohormesis: promoting health and lifespan by increased levels of reactive oxygen species (ROS)

M Ristow, K Schmeisser - Dose-response, 2014 - journals.sagepub.com
Increasing evidence indicates that reactive oxygen species (ROS), consisting of superoxide,
hydrogen peroxide, and multiple others, do not only cause oxidative stress, but rather may …