Exercise intolerance, benefits, and prescription for people living with a Fontan circulation: the Fontan Fitness Intervention Trial (F-FIT)—rationale and design

DL Tran, H Gibson, AJ Maiorana, CE Verrall… - Frontiers in …, 2022 - frontiersin.org
Background: Despite developments in surgical techniques and medical care, people with a
Fontan circulation still experience long-term complications; non-invasive therapies to …

Hypoplastic left heart syndrome (HLHS): molecular pathogenesis and emerging drug targets for cardiac repair and regeneration

AT Bejjani, N Wary, M Gu - Expert opinion on therapeutic targets, 2021 - Taylor & Francis
Introduction Hypoplastic left heart syndrome (HLHS) is a severe developmental defect
characterized by the underdevelopment of the left ventricle along with aortic and valvular …

Natural and modified history of atrioventricular valve regurgitation in patients with Fontan circulation

G King, E Buratto, DS Celermajer, L Grigg… - Journal of the American …, 2022 - jacc.org
Background Atrioventricular valve (AVV) regurgitation is increasingly prevalent in patients
with a Fontan circulation. Objectives We sought to determine the impact of ventricular …

Ventricular morphology of single-ventricle hearts has a significant impact on outcomes after Fontan palliation: a meta-analysis

M Ponzoni, D Azzolina, L Vedovelli… - European Journal of …, 2022 - academic.oup.com
OBJECTIVES A conclusive interpretation of the role of ventricular dominance in outcomes
after Fontan palliation has not been formulated yet. We conducted a systematic review and …

Integrated clinical and magnetic resonance imaging assessments late after Fontan operation

SL Meyer, N St. Clair, AJ Powell, T Geva… - Journal of the American …, 2021 - jacc.org
Background Several clinical and cardiac magnetic resonance (CMR)-derived parameters
have been shown to be associated with death or heart transplant late after the Fontan …

Left atrial stiffness and strain are novel indices of left ventricular diastolic function in children: validation followed by application in multisystem inflammatory syndrome …

JC Zuckerberg, D Matsubara… - European Heart …, 2023 - academic.oup.com
Aims We hypothesized left atrial (LA) stiffness may serve as a surrogate marker in children to
differentiate elevated pulmonary capillary wedge pressure (PCWP) from normal and help …

[HTML][HTML] Fontan with lateral tunnel is associated with improved survival compared with extracardiac conduit

VHM Weixler, D Zurakowski, J Kheir… - The Journal of Thoracic …, 2020 - Elsevier
Objectives The study aim was to compare Fontan patients undergoing lateral tunnel (LT)
versus extracardiac conduit (ECC) technique. Methods Fontan patients (LT vs ECC) from …

[HTML][HTML] Serial cardiovascular magnetic resonance feature tracking indicates early worsening of cardiac function in Fontan patients

SL Meyer, FJS Ridderbos, D Wolff, G Eshuis… - International Journal of …, 2020 - Elsevier
Abstract Background In Fontan patients, attrition of ventricular function is well recognized,
but early detection of ventricular dysfunction is difficult. The aim of this study is to …

[HTML][HTML] Longitudinal changes in ventricular size and function are associated with death and transplantation late after the Fontan operation

SJ Ghelani, M Lu, LA Sleeper, A Prakash… - Journal of …, 2022 - Elsevier
Background Cross-sectional studies have reported that ventricular dilation and dysfunction
are associated with adverse clinical outcome in Fontan patients; however, longitudinal …

Dominant ventricular morphology and early postoperative course after the Fontan procedure

U Pollak, I Abarbanel, Y Salem… - World Journal for …, 2022 - journals.sagepub.com
Background Single ventricle heart disease comprises a wide variety of critical heart defects
that lead to the provision of systemic cardiac output by one dominant ventricle. It requires …