At present, much attention is paid to the use of antimicrobial peptides (AMPs) of natural and
artificial origin to combat pathogens. AMPs have several points that determine their …

Protein aggregation is responsible for various human diseases, ie Alzheimer's, Parkinson's,
Huntington's as well as cataract. Finding molecular drugs which could prevent protein …

Proteins are major components of the biological functions in a cell. Biology demands that a
protein must fold into its stable three-dimensional structure to become functional. In an …

Abstract Cyclin-dependent kinase 5 (CDK5), an atypical member of the cyclin-dependent
kinase family, plays an important role in the nervous system. Recent studies have shown …

A giant multidomain protein of striated and smooth vertebrate muscles, titin, consists of
tandems of immunoglobulin (Ig)-and fibronectin type III (FnIII)-like domains representing β …

A comparative study of amyloid properties of the aggregates of smooth muscle titin (SMT)
from chicken gizzard was carried out. These aggregates were formed in two solutions: 0.15 …

Various amyloid aggregates, in particular, aggregates of amyloid β-proteins, demonstrate in
vitro and in vivo cytotoxic effects associated with impairment of cell adhesion. We …

This work investigated in vitro aggregation and amyloid properties of skeletal myosin
binding protein-C (sMyBP-C) interacting in vivo with proteins of thick and thin filaments in the …

In this paper, the property of the muscle titin protein to form in vitro specific amyloid-like
aggregates is discussed. The main difference from the known amyloid aggregates is the …

Titin is a multidomain protein of striated and smooth muscles of vertebrates. The protein
consists of repeating immunoglobulin-like (Ig) and fibronectin-like (FnIII) domains, which are …