[HTML][HTML] Osteoarthritis in year 2021: biochemical markers

Y Henrotin - Osteoarthritis and cartilage, 2022 - Elsevier
Objective To summarize recent scientific advances in protein-derived soluble biomarkers of
osteoarthritis. Design A systematic search on the PubMed electronic database of clinical …

Blood and urine biomarkers in osteoarthritis–an update on cartilage associated type II collagen and aggrecan markers

AC Bay-Jensen, A Mobasheri… - Current opinion in …, 2022 - journals.lww.com
Blood and urine biomarkers in osteoarthritis – an update on... : Current Opinion in Rheumatology
Blood and urine biomarkers in osteoarthritis – an update on cartilage associated type II collagen …

Osteoarthritis endotype discovery via clustering of biochemical marker data

F Angelini, P Widera, A Mobasheri, J Blair… - Annals of the …, 2022 - ard.bmj.com
Objectives Osteoarthritis (OA) patient stratification is an important challenge to design
tailored treatments and drive drug development. Biochemical markers reflecting joint tissue …

Osteoarthritis as an umbrella term for different subsets of humans undergoing joint degeneration: The need to address the differences to develop effective …

DA Hart - International Journal of Molecular Sciences, 2022 - mdpi.com
Osteoarthritis (OA) of joints such as the knee and hip are very prevalent, and the number of
individuals affected is expected to continue to rise. Currently, conservative treatments after …

[HTML][HTML] Soluble biomarkers in osteoarthritis in 2022: year in review

FAC Rocha, SA Ali - Osteoarthritis and Cartilage, 2023 - Elsevier
Objective To review articles reporting on the development of soluble biomarkers in
osteoarthritis (OA) over the past year. Design Two literature searches were conducted using …

Emerging molecular biomarkers in osteoarthritis pathology

A Sandhu, JS Rockel, S Lively… - Therapeutic Advances …, 2023 - journals.sagepub.com
Osteoarthritis (OA) is the most common form of arthritis resulting in joint discomfort and
disability, culminating in decline in life quality. Attention has been drawn in recent years to …

Strategic outline of interventions targeting extracellular matrix for promoting healthy longevity

JYC Park, A King, V Björk, BW English… - … of Physiology-Cell …, 2023 - journals.physiology.org
The extracellular matrix (ECM), composed of interlinked proteins outside of cells, is an
important component of the human body that helps maintain tissue architecture and cellular …

A matrix metalloproteinase-generated neoepitope of CRP can identify knee and multi-joint inflammation in osteoarthritis

LC Alexander Jr, G McHorse, JL Huebner… - Arthritis Research & …, 2021 - Springer
Objective To compare C-reactive protein (CRP) and matrix metalloproteinase-generated
neoepitope of CRP (CRPM) as biomarkers of inflammation and radiographic severity in …

An osteoarthritis pathophysiological continuum revealed by molecular biomarkers

VB Kraus, S Sun, A Reed, EJ Soderblom… - Science …, 2024 - science.org
We aimed to identify serum biomarkers that predict knee osteoarthritis (OA) before the
appearance of radiographic abnormalities in a cohort of 200 women. As few as six serum …

From biochemical markers to molecular endotypes of osteoarthritis: a review on validated biomarkers

MT Hannani, CS Thudium, MA Karsdal… - Expert Review of …, 2024 - Taylor & Francis
Introduction Osteoarthritis (OA) affects over 500 million people worldwide. OA patients are
symptomatically treated, and current therapies exhibit marginal efficacy and frequently carry …