Derivatization for liquid chromatography-mass spectrometry

BL Qi, P Liu, QY Wang, WJ Cai, BF Yuan… - TrAC Trends in Analytical …, 2014 - Elsevier
Liquid chromatography-mass spectrometry (LC-MS) is one of the most prominent analytical
techniques, due to its inherent selectivity and sensitivity. In LC-MS, chemical derivatizations …

Derivatization of steroids in biological samples for GC–MS and LC–MS analyses

J Marcos, OJ Pozo - Bioanalysis, 2015 - Taylor & Francis
The determination of steroids in biological samples is essential in different areas of
knowledge. MS combined with either GC or LC is considered the best analytical technique …

Improved ion mobility separation and structural characterization of steroids using derivatization methods

DC Velosa, AJ Dunham, ME Rivera… - Journal of the …, 2022 - ACS Publications
Steroids are an important class of biomolecules studied for their role in metabolism,
development, nutrition, and disease. Although highly sensitive GC-and LC-MS/MS-based …

Derivatization methods for quantitative bioanalysis by LC–MS/MS

P Deng, Y Zhan, X Chen, D Zhong - Bioanalysis, 2012 - Taylor & Francis
LC with atmospheric pressure ionization MS is essential to a large number of quantitative
bioanalyses for a variety of compounds, especially nonvolatile or highly polar compounds …

Derivatization methods for LC–MS analysis of endogenous compounds

Y Zhu, P Deng, D Zhong - Bioanalysis, 2015 - Taylor & Francis
Sensitive and reliable analysis of endogenous compounds is critically important for many
physiological and pathological studies. Methods based on LC–MS have progressed to …

Early Life-Stage Toxicity of Eight Pharmaceuticals to the Fathead Minnow, Pimephales promelas

MD Overturf, CL Overturf, D Baxter, DN Hala… - Archives of …, 2012 - Springer
Human pharmaceuticals are routinely being detected in the environment, and there is
growing concern about whether these drugs could elicit effects on aquatic organisms …

A novel diarylethene-hydrazinopyridine-based probe for fluorescent detection of aluminum ion and naked-eye detection of hydroxide ion

SY Li, DB Zhang, JY Wang, RM Lu, CH Zheng… - Sensors and Actuators B …, 2017 - Elsevier
A novel photochromic diarylethene derivative 1o with hydrazinopyridine as a functional
group was designed and synthesized. It had multi-responsively photoswitchable properties …

Derivatization, an applicable asset for conventional HPLC systems without MS detection in food and miscellaneous analysis

R Dogra, M Kumar, A Kumar, M Roverso… - Critical Reviews in …, 2023 - Taylor & Francis
One of the most valuable practices for analyzing not-so-analytical-friendly analytes in
complex, heterogenous matrices is derivatization. Availability of numerous derivatizing …

Analytics for steroid hormone profiling in body fluids

A Temerdashev, E Dmitrieva, I Podolskiy - Microchemical Journal, 2021 - Elsevier
The present article focuses on the most commonly used and perspective methods (including
non-chromatographic assays) for steroids quantification in different matrices. The main …

Levonorgestrel exposure to fathead minnows (Pimephales promelas) alters survival, growth, steroidogenic gene expression and hormone production

MD Overturf, CL Overturf, DR Carty, D Hala… - Aquatic toxicology, 2014 - Elsevier
Human pharmaceuticals are commonly detected in the environment. Concern over these
compounds in the environment center around the potential for pharmaceuticals to interfere …