Nucleus segmentation: towards automated solutions
Single nucleus segmentation is a frequent challenge of microscopy image processing, since
it is the first step of many quantitative data analysis pipelines. The quality of tracking single …
it is the first step of many quantitative data analysis pipelines. The quality of tracking single …
Replacement, reduction, and refinement of animal experiments in anticancer drug development: the contribution of 3D in vitro cancer models in the drug efficacy …
In the last decades three-dimensional (3D) in vitro cancer models have been proposed as a
bridge between bidimensional (2D) cell cultures and in vivo animal models, the gold …
bridge between bidimensional (2D) cell cultures and in vivo animal models, the gold …
[HTML][HTML] Software tools for 3D nuclei segmentation and quantitative analysis in multicellular aggregates
Today, we are fully immersed into the era of 3D biology. It has been extensively
demonstrated that 3D models:(a) better mimic the physiology of human tissues;(b) can …
demonstrated that 3D models:(a) better mimic the physiology of human tissues;(b) can …
Marker-controlled watershed with deep edge emphasis and optimized H-minima transform for automatic segmentation of densely cultivated 3D cell nuclei
T Kaseva, B Omidali, E Hippeläinen, T Mäkelä… - BMC …, 2022 - Springer
Background The segmentation of 3D cell nuclei is essential in many tasks, such as targeted
molecular radiotherapies (MRT) for metastatic tumours, toxicity screening, and the …
molecular radiotherapies (MRT) for metastatic tumours, toxicity screening, and the …
3D-Cell-Annotator: an open-source active surface tool for single-cell segmentation in 3D microscopy images
Segmentation of single cells in microscopy images is one of the major challenges in
computational biology. It is the first step of most bioimage analysis tasks, and essential to …
computational biology. It is the first step of most bioimage analysis tasks, and essential to …
ReViMS: Software tool for estimating the volumes of 3-D multicellular spheroids imaged using a light sheet fluorescence microscope
Cancer 3-D spheroids are widely used to test drugs and radiotherapy treatments. These 3-D
cell clusters range from tens to hundreds of micrometers in size, with shapes that typically …
cell clusters range from tens to hundreds of micrometers in size, with shapes that typically …
Two-dimensional segmentation fusion tool: an extensible, free-to-use, user-friendly tool for combining different bidimensional segmentations
Introduction: In several fields, the process of fusing multiple two-dimensional (2D) closed
lines is an important step. For instance, this is fundamental in histology and oncology in …
lines is an important step. For instance, this is fundamental in histology and oncology in …
A review of open-source image analysis tools for mammalian cell culture: algorithms, features and implementations
Cell culture is undeniably important for multiple scientific applications, including
pharmaceuticals, transplants, and cosmetics. However, cell culture involves multiple manual …
pharmaceuticals, transplants, and cosmetics. However, cell culture involves multiple manual …
Quantitative Analysis of Whole-Mount Fluorescence-Stained Tumor Spheroids in Phenotypic Drug Screens
E Nuernberg, R Bruch, M Hafner, R Rudolf… - 3D Cell Culture …, 2024 - Springer
Three-dimensional cell cultures, such as spheroids or organoids, serve as important models
for drug screening purposes. Optical tissue clearing (OTC) enhances the visualization of …
for drug screening purposes. Optical tissue clearing (OTC) enhances the visualization of …
Check for updates Chapter 19 Real-Time Cell Cycle Imaging in a 3D Cell Culture Model of Melanoma, Quantitative Analysis, Optical Clearing, and Mathematical …
L Spoerri, KA Beaumont, A Anfosso… - 3D Cell Culture …, 2024 - books.google.com
Aberrant cell cycle progression is a hallmark of solid tumors. Therefore, cell cycle analysis is
an invaluable technique to study cancer cell biology. However, cell cycle progression has …
an invaluable technique to study cancer cell biology. However, cell cycle progression has …