Analysis of thermal melting curves

JL Mergny, L Lacroix - Oligonucleotides, 2003 - liebertpub.com
Tm is defined as Temperature of melting or, more accurately, as temperature of
midtransition. This term is often used for nucleic acids (DNA and RNA, oligonucleotides and …

Physics of base-pairing dynamics in DNA

M Manghi, N Destainville - Physics Reports, 2016 - Elsevier
As a key molecule of life, Deoxyribo-Nucleic Acid (DNA) is the focus of numbers of
investigations with the help of biological, chemical and physical techniques. From a physical …

uMELT: prediction of high-resolution melting curves and dynamic melting profiles of PCR products in a rich web application

Z Dwight, R Palais, CT Wittwer - Bioinformatics, 2011 - academic.oup.com
uMelt SM is a flexible web-based tool for predicting DNA melting curves and denaturation
profiles of PCR products. The user defines an amplicon sequence and chooses a set of …

Generic eukaryotic core promoter prediction using structural features of DNA

T Abeel, Y Saeys, E Bonnet, P Rouzé… - Genome …, 2008 - genome.cshlp.org
Despite many recent efforts, in silico identification of promoter regions is still in its infancy.
However, the accurate identification and delineation of promoter regions is important for …

Multi-spectroscopic and molecular modeling studies to reveal the interaction between propyl acridone and calf thymus DNA in the presence of histone H1: Binary and …

N Shakibapour, F Dehghani Sani… - Journal of …, 2019 - Taylor & Francis
DNA is the primary target of many anticancer drugs involved in important intercellular
processes, especially in transcriptional regulation, and histone is known to inhibit gene …

Roles of stiffness and excluded volume in DNA denaturation

E Carlon, E Orlandini, AL Stella - Physical review letters, 2002 - APS
The nature and the universal properties of DNA thermal denaturation are investigated by
Monte Carlo simulations. For suitable lattice models we determine the exponent c describing …

Large-scale structural analysis of the core promoter in mammalian and plant genomes

K Florquin, Y Saeys, S Degroeve, P Rouze… - Nucleic acids …, 2005 - academic.oup.com
DNA encodes at least two independent levels of functional information. The first level is for
encoding proteins and sequence targets for DNA-binding factors, while the second one is …

Modified oligonucleotides for mismatch discrimination

RO Dempcy, AA Gall, SG Lokhov, IA Afonina… - US Patent …, 2006 - Google Patents
US7045610B2 - Modified oligonucleotides for mismatch discrimination - Google Patents
US7045610B2 - Modified oligonucleotides for mismatch discrimination - Google Patents …

β sheets not required: Combined experimental and computational studies of self-assembly and gelation of the ester-containing analogue of an Fmoc-dipeptide …

KM Eckes, X Mu, MA Ruehle, P Ren, LJ Suggs - Langmuir, 2014 - ACS Publications
In our work toward developing ester-containing self-assembling peptides as soft
biomaterials, we have found that a fluorenylmethoxycarbonyl (Fmoc)-conjugated alanine …

Bubble nucleation and cooperativity in DNA melting

Y Zeng, A Montrichok, G Zocchi - Journal of molecular biology, 2004 - Elsevier
Bubbles in DNA are related to fundamental processes such as duplication and transcription.
Using a new ensemble technique to trap intermediate states, we present direct …