Mechanisms of lncRNA/microRNA interactions in angiogenesis

Z Zhao, W Sun, Z Guo, J Zhang, H Yu, B Liu - Life sciences, 2020 - Elsevier
Angiogenesis is a complex physiological process. However, over the past couple of
decades, abnormally accelerated or pathological angiogenesis has garnered greater …

[HTML][HTML] Targeting the oncogenic transcription factor FOXM1 to improve outcomes in all subtypes of breast cancer

BS Katzenellenbogen, VS Guillen… - Breast Cancer …, 2023 - Springer
Abstract FOXM1 (Forkhead box M1) is an oncogenic transcription factor that is greatly
upregulated in breast cancer and many other cancers where it promotes tumorigenesis, and …

FOXM1: From cancer initiation to progression and treatment

CY Koo, KW Muir, EWF Lam - Biochimica et Biophysica Acta (BBA)-Gene …, 2012 - Elsevier
The Forkhead box protein M1 (FOXM1) transcription factor is a regulator of myriad biological
processes, including cell proliferation, cell cycle progression, cell differentiation, DNA …

Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds

MK Shanmugam, JH Lee, EZP Chai, MM Kanchi… - Seminars in cancer …, 2016 - Elsevier
The association between chronic inflammation and cancer development has been well
documented. One of the major obstacles in cancer treatment is the persistent autocrine and …

[HTML][HTML] Critical role of O-Linked β-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis

TP Lynch, CM Ferrer, SRE Jackson… - Journal of Biological …, 2012 - ASBMB
Cancer cells universally increase glucose and glutamine consumption, leading to the
altered metabolic state known as the Warburg effect; one metabolic pathway, highly …

FOXM1 promotes the warburg effect and pancreatic cancer progression via transactivation of LDHA expression

J Cui, M Shi, D Xie, D Wei, Z Jia, S Zheng, Y Gao… - Clinical Cancer …, 2014 - AACR
Abstract Purpose: The transcription factor Forkhead box protein M1 (FOXM1) plays critical
roles in cancer development and progression. However, the regulatory role and underlying …

FOX (M1) news—it is cancer

M Halasi, AL Gartel - Molecular cancer therapeutics, 2013 - AACR
FOXM1 is an oncogenic transcription factor of the Forkhead family and it has a well-defined
role in cell proliferation and cell-cycle progression. Expression of FOXM1 is excluded in …

FoxM1: Repurposing an oncogene as a biomarker

D Nandi, PS Cheema, N Jaiswal, A Nag - Seminars in Cancer Biology, 2018 - Elsevier
The past few decades have witnessed a tremendous progress in understanding the biology
of cancer, which has led to more comprehensive approaches for global gene expression …

Over‐expression of FoxM1 leads to epithelial–mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells

B Bao, Z Wang, S Ali, D Kong… - Journal of cellular …, 2011 - Wiley Online Library
FoxM1 is known to play important role in the development and progression of many
malignancies including pancreatic cancer. Studies have shown that the acquisition of …

[HTML][HTML] Long noncoding RNA TRPM2-AS acts as a microRNA sponge of miR-612 to promote gastric cancer progression and radioresistance

J Xiao, L Lin, D Luo, L Shi, W Chen, H Fan, Z Li, X Ma… - Oncogenesis, 2020 - nature.com
Long noncoding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis
and are frequently dysregulated in cancers. Here, we identify a critical lncRNA TRPM2-AS …