SARS-CoV-2 spike S2-specific neutralizing antibodies

CJ Li, SC Chang - Emerging Microbes & Infections, 2023 - Taylor & Francis
Since the onset of the coronavirus disease 2019 (COVID-19), numerous neutralizing
antibodies (NAbs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Broadly neutralizing antibodies target the coronavirus fusion peptide

C Dacon, C Tucker, L Peng, CCD Lee, TH Lin, M Yuan… - Science, 2022 - science.org
The potential for future coronavirus outbreaks highlights the need to broadly target this
group of pathogens. We used an epitope-agnostic approach to identify six monoclonal …

Inducing broad-based immunity against viruses with pandemic potential

A Sette, EO Saphire - Immunity, 2022 - cell.com
The brutal toll of another viral pandemic can be blunted by investing now in research that
uncovers mechanisms of broad-based immunity so we may have vaccines and therapeutics …

Both Feline Coronavirus Serotypes 1 and 2 Infected Domestic Cats Develop Cross-Reactive Antibodies to SARS-CoV-2 Receptor Binding Domain: Its Implication to …

JK Yamamoto, LK Edison, DK Rowe-Haas, T Takano… - Viruses, 2023 - mdpi.com
The current study was initiated when our specific-pathogen-free laboratory toms developed
unexpectedly high levels of cross-reactive antibodies to human SARS-CoV-2 (SCoV2) …

Impact of SARS-CoV-2 spike mutations on its activation by TMPRSS2 and the alternative TMPRSS13 protease

A Stevaert, R Van Berwaer, C Mestdagh, J Vandeput… - Mbio, 2022 - Am Soc Microbiol
The continuous emergence of new variants of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) urges better understanding of the functional motifs in the spike …

Current status and perspectives of therapeutic antibodies targeting the spike protein S2 subunit against SARS-CoV-2

Y Yamamoto, T Inoue - Biological and Pharmaceutical Bulletin, 2024 - jstage.jst.go.jp
The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has devastated public health and the …

[HTML][HTML] Validation of a plasmonic-based serology biosensor for veterinary diagnosis of COVID-19 in domestic animals

JF Giarola, M Soler, MC Estevez, A Tarasova… - Talanta, 2024 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic recently demonstrated the
devastating impact on public health, economy, and social development of zoonotic …

[HTML][HTML] Cellular electrical impedance to profile SARS-CoV-2 fusion inhibitors and to assess the fusogenic potential of spike mutants

E Vanhulle, J Doijen, J Stroobants, B Provinciael… - Antiviral Research, 2023 - Elsevier
Despite the vaccination campaigns for COVID-19, we still cannot control the spread of SARS-
CoV-2, as evidenced by the ongoing circulation of the Omicron variants of concern. This …

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that bind a conserved membrane proximal epitope of the spike

S De Cae, I Van Molle, L van Schie, SR Shoemaker… - bioRxiv, 2023 - biorxiv.org
Currently circulating SARS-CoV-2 variants have gained complete or significant resistance to
all SARS-CoV-2-neutralizing antibodies that have been used in the clinic. Such antibodies …

[HTML][HTML] An octavalent dendrimer of multiple antigenic peptide with a property of pan-coronavirus IgM induction improved clinical signs of feline infectious peritonitis in …

T Nara, H Shimoda, C Suzuki, NTB Tran, H Tsukada… - Veterinary Vaccine, 2024 - Elsevier
Feline infectious peritonitis (FIP) is a lethal disease caused by a pathogenic coronavirus,
feline infectious peritonitis virus (FIPV), in cats. Effective vaccines have been unsuccessful …