In recent decades, the worldwide prevalence of allergic disease has increased
considerably. The atopic march is a model aimed at explaining the apparent progression of …

Background In China, childhood asthma prevalence showed a remarkable increase in the
past decades. An updated epidemiological assessment of childhood asthma in China with a …

Rationale: Women have a higher burden of asthma than men. Although sex hormones may
explain sex differences in asthma, their role is unclear. Objectives: To examine sex hormone …

Background Kidney function declines faster in men. Testosterone levels may mediate the
sex disparity. Correspondingly, levels of sex hormone binding globulin (SHBG), which …

目的分析1990-2019 年我国1~ 19 岁儿童青少年哮喘疾病负担及其变化趋势,
为优化儿童青少年哮喘的健康管理提供依据. 方法利用2019 年全球疾病负担中国分省研究结果 …

Background Several risk factors for asthma have been proposed; however, the causality of
these associations is sometimes unclear. Mendelian randomization is a powerful …

Background Hospitalisation for bronchiolitis is a risk factor for asthma and impaired lung
function during childhood, but outcomes in young adults are poorly described. Our primary …

Background Although observational studies have shown an association between sex
hormone-binding globulin (SHBG), testosterone (T) and cardiovascular diseases (CVD) …

A gender-related disparity exists in asthma morbidity and mortality, which shifts at around
puberty from a male predominance to a female predominance. This is clinically reflected in …

The recent progress in clarifying the connections between childhood obesity and asthma
and their combined impacts on immune function moves us closer to the goals of improved …