PfEMP1–a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis
L Hviid, ATR Jensen - Advances in parasitology, 2015 - Elsevier
Plasmodium falciparum causes the most severe form of malaria and is responsible for
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …
First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria
B Mordmüller, M Sulyok, D Egger-Adam… - Clinical Infectious …, 2019 - academic.oup.com
Background Malaria in pregnancy has major impacts on mother and child health. To
complement existing interventions, such as intermittent preventive treatment and use of …
complement existing interventions, such as intermittent preventive treatment and use of …
Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children
T Lavstsen, L Turner, F Saguti… - Proceedings of the …, 2012 - National Acad Sciences
The clinical outcome of Plasmodium falciparum infections ranges from asymptomatic
parasitemia to severe malaria syndromes associated with high mortality. The virulence of P …
parasitemia to severe malaria syndromes associated with high mortality. The virulence of P …
Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria
TM Clausen, S Christoffersen, M Dahlbäck… - Journal of Biological …, 2012 - ASBMB
Malaria is a major global health problem. Pregnant women are susceptible to infection
regardless of previously acquired immunity. Placental malaria is caused by parasites …
regardless of previously acquired immunity. Placental malaria is caused by parasites …
VAR2CSA-Mediated Host Defense Evasion of Plasmodium falciparum Infected Erythrocytes in Placental Malaria
A Tomlinson, JP Semblat, B Gamain… - Frontiers in …, 2021 - frontiersin.org
Over 30 million women living in P. falciparum endemic areas are at risk of developing
malaria during pregnancy every year. Placental malaria is characterized by massive …
malaria during pregnancy every year. Placental malaria is characterized by massive …
Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA
R Ma, T Lian, R Huang, JP Renn, JD Petersen… - Nature …, 2021 - nature.com
Plasmodium falciparum VAR2CSA binds to chondroitin sulfate A (CSA) on the surface of the
syncytiotrophoblast during placental malaria. This interaction facilitates placental …
syncytiotrophoblast during placental malaria. This interaction facilitates placental …
The progression of the intra-erythrocytic cell cycle of Plasmodium falciparum and the role of the centriolar plaques in asynchronous mitotic division during schizogony
DE Arnot, E Ronander, DC Bengtsson - International journal for …, 2011 - Elsevier
The cell division cycle and mitosis of intra-erythrocytic (IE) Plasmodium falciparum are
poorly understood aspects of parasite development which affect malaria molecular …
poorly understood aspects of parasite development which affect malaria molecular …
Surface Co-Expression of Two Different PfEMP1 Antigens on Single Plasmodium falciparum-Infected Erythrocytes Facilitates Binding to ICAM1 and PECAM1
L Joergensen, DC Bengtsson, A Bengtsson… - PLoS …, 2010 - journals.plos.org
The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigens play a
major role in cytoadhesion of infected erythrocytes (IE), antigenic variation, and immunity to …
major role in cytoadhesion of infected erythrocytes (IE), antigenic variation, and immunity to …
Early gametocytes of the malaria parasite Plasmodium falciparum specifically remodel the adhesive properties of infected erythrocyte surface
M Tibúrcio, F Silvestrini, L Bertuccini… - Cellular …, 2013 - Wiley Online Library
In P lasmodium falciparum infections the parasite transmission stages, the gametocytes,
mature in 10 days sequestered in internal organs. Recent studies suggest that cell …
mature in 10 days sequestered in internal organs. Recent studies suggest that cell …
Global genetic diversity of var2csa in Plasmodium falciparum with implications for malaria in pregnancy and vaccine development
ED Benavente, DR Oresegun, PF de Sessions… - Scientific Reports, 2018 - nature.com
Malaria infection during pregnancy, caused by the sequestering of Plasmodium falciparum
parasites in the placenta, leads to high infant mortality and maternal morbidity. The parasite …
parasites in the placenta, leads to high infant mortality and maternal morbidity. The parasite …