Novel metabolic and physiological functions of branched chain amino acids: a review

S Zhang, X Zeng, M Ren, X Mao, S Qiao - Journal of animal science and …, 2017 - Springer
It is widely known that branched chain amino acids (BCAA) are not only elementary
components for building muscle tissue but also participate in increasing protein synthesis in …

A brief review of critical processes in exercise-induced muscular hypertrophy

SM Phillips - Sports Medicine, 2014 - Springer
With regular practice, resistance exercise can lead to gains in skeletal muscle mass by
means of hypertrophy. The process of skeletal muscle fiber hypertrophy comes about as a …

Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men

Y Yang, L Breen, NA Burd, AJ Hector… - British Journal of …, 2012 - cambridge.org
Feeding stimulates robust increases in muscle protein synthesis (MPS); however, ageing
may alter the anabolic response to protein ingestion and the subsequent aminoacidaemia …

[HTML][HTML] A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly

CS Katsanos, H Kobayashi… - American Journal …, 2006 - journals.physiology.org
This study was designed to evaluate the effects of enriching an essential amino acid (EAA)
mixture with leucine on muscle protein metabolism in elderly and young individuals. Four (2 …

[HTML][HTML] Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults

E Volpi, H Kobayashi, M Sheffield-Moore… - The American journal of …, 2003 - Elsevier
Background Nutritional supplementation may be used to treat muscle loss with aging
(sarcopenia). However, if physical activity does not increase, the elderly tend to compensate …

Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise …

TA Churchward‐Venne, NA Burd… - The Journal of …, 2012 - Wiley Online Library
Key points• Essential amino acids (EAAs) stimulate increased rates of myofibrillar protein
synthesis (MPS).• Leucine is a key regulator of MPS in rodents; however, its importance …

Skeletal muscle protein metabolism in the elderly: Interventions to counteract the'anabolic resistance'of ageing

L Breen, SM Phillips - Nutrition & metabolism, 2011 - Springer
Age-related muscle wasting (sarcopenia) is accompanied by a loss of strength which can
compromise the functional abilities of the elderly. Muscle proteins are in a dynamic …

Dietary protein requirements and adaptive advantages in athletes

SM Phillips - British Journal of Nutrition, 2012 - cambridge.org
Dietary guidelines from a variety of sources are generally congruent that an adequate
dietary protein intake for persons over the age of 19 is between 0· 8–0· 9 g protein/kg body …

[HTML][HTML] Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis

SR Kimball, LS Jefferson - The Journal of nutrition, 2006 - Elsevier
BCAAs stimulate protein synthesis in in vitro preparations of skeletal muscle. Likewise, the
stimulation of protein synthesis in skeletal muscle produced by intake of a mixed meal is due …

[HTML][HTML] Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise

LE Norton, DK Layman - The Journal of nutrition, 2006 - Elsevier
High-performance physical activity and postexercise recovery lead to significant changes in
amino acid and protein metabolism in skeletal muscle. Central to these changes is an …