The corneal wound healing response is typically initiated by injuries to the epithelium and/or
endothelium that may also involve the stroma. However, it can also be triggered by immune …

Abstract The TGF beta-1,-2 and-3 isoforms are transcribed from different genes but bind to
the same receptors and signal through the same canonical and non-canonical signal …

Myofibroblasts are alpha-smooth muscle actin (SMA)+ cells that have a critical role in the
corneal stromal response to infections, injuries, and surgeries, and which produce corneal …

Losartan is an angiotensin II receptor blocker (ARB) that impedes transforming growth factor
(TGF) beta signaling by inhibiting activation of signal transduction molecule extracellular …

Basement membranes are highly specialized extracellular matrices. More than providing
scaffolds, basement membranes are recognized as dynamic and versatile structures that …

The ocular surface, which forms the interface between the eye and the external environment,
includes the cornea, corneoscleral limbus, the conjunctiva and the accessory glands that …

The purpose of this study was to investigate the expression and localization of transforming
growth factor (TGF) β1 and TGFβ2 in rabbit corneas that healed with and without stromal …

Purpose: Interleukin (IL)-1α/IL-1β and transforming growth factor (TGF) β1/TGFβ2 have both
been promoted as “master regulators” of the corneal wound healing response due to the …

The purpose of this investigation was to study Descemet's membrane and corneal
endothelial regeneration, myofibroblast generation and disappearance, and TGF beta-1 …

PURPOSE: To study epithelial basement membrane (EBM) regeneration in non-fibrotic and
fibrotic corneas after photorefractive keratectomy (PRK). METHODS: Rabbits (120 total) had …