Inductively coupled plasma–mass spectrometry (ICP-MS) for quantitative analysis in environmental and life sciences: a review of challenges, solutions, and trends

D Pröfrock, A Prange - Applied spectroscopy, 2012 - journals.sagepub.com
This focal point review provides an overview of recent developments and capabilities of
inductively coupled plasma mass spectrometry (ICPMS) coupled with different separation …

The emerging role of ICP-MS in proteomic analysis

J Bettmer, MM Bayón, JR Encinar, MLF Sánchez… - Journal of …, 2009 - Elsevier
Quantitative proteomics and absolute determination of proteins are topics of fast growing
interest, since only the quantity of proteins or changes in their abundance reflect the status …

Triple quad ICPMS (ICPQQQ) as a new tool for absolute quantitative proteomics and phosphoproteomics

SD Fernández, N Sugishama, JR Encinar… - Analytical …, 2012 - ACS Publications
It is clear that sensitive and interference-free quantification of ICP-detectable elements
naturally present in proteins will boost the role of ICPMS in proteomics. In this study, a …

Metallothioneins and cancer

T Eckschlager, V Adam, J Hrabeta… - Current Protein and …, 2009 - ingentaconnect.com
Metallothioneins (MTs) are low molecular, cysteine-rich proteins that have naturally-
occurring Zn2+ in both clusters. They may serve as a reservoir of metals for synthesis of …

ICP‐MS‐based strategies for protein quantification

M Wang, WY Feng, YL Zhao… - Mass spectrometry …, 2010 - Wiley Online Library
In the post‐genomics era, proteomics has become a central branch in life sciences. An
understanding of biological functions will not only rely on protein identification, but also on …

Chemical labels and natural element tags for the quantitative analysis of bio-molecules

A Prange, D Pröfrock - Journal of Analytical Atomic Spectrometry, 2008 - pubs.rsc.org
Besides the qualitative analysis of a bio-molecule or even a whole proteome, their
quantitative determination is also a topic of growing interest, since only the quantity of …

Establishment of measurement traceability for peptide and protein quantification through rigorous purity assessment—a review

RD Josephs, G Martos, M Li, L Wu, JE Melanson… - Metrologia, 2019 - iopscience.iop.org
The health of their populations and efficient health care systems are of critical importance to
the economic and social well-being of nations. Accurate and comparable peptide/protein …

ICP-MS for absolute quantification of proteins for heteroatom-tagged, targeted proteomics

A Sanz-Medel, M Montes-Bayón, J Bettmer… - TrAC Trends in …, 2012 - Elsevier
Detection with inductively coupled plasma mass spectrometry (ICP-MS) holds great promise
in tackle the challenge of absolute, reliable quantification of proteins and peptides. We …

Elemental mass spectrometry for quantitative proteomics

A Sanz-Medel, M Montes-Bayón… - Analytical and …, 2008 - Springer
In the last decade mass-spectrometry-based proteomics has become an indispensable
analytical tool for molecular biology, cellular biology and, lately, for the emerging systems …

Sulfur analysis by inductively coupled plasma-mass spectrometry: A review

JG Martínez-Sierra, OG San Blas, JMM Gayón… - … Acta Part B: Atomic …, 2015 - Elsevier
In recent years the number of applications of sulfur (S) analysis using inductively coupled
plasma mass spectrometry (ICP-MS) as detector has increased significantly. In this article …