Inflammation and brain structure in schizophrenia and other neuropsychiatric disorders: a Mendelian randomization study
Importance Previous in vitro and postmortem research suggests that inflammation may lead
to structural brain changes via activation of microglia and/or astrocytic dysfunction in a range …
to structural brain changes via activation of microglia and/or astrocytic dysfunction in a range …
[HTML][HTML] Inflammatory subgroups of schizophrenia and their association with brain structure: A semi-supervised machine learning examination of heterogeneity
Objective Immune system dysfunction is hypothesised to contribute to structural brain
changes through aberrant synaptic pruning in schizophrenia. However, evidence is mixed …
changes through aberrant synaptic pruning in schizophrenia. However, evidence is mixed …
Perturbed iron biology in the prefrontal cortex of people with schizophrenia
Despite loss of grey matter volume and emergence of distinct cognitive deficits in young
adults diagnosed with schizophrenia, current treatments for schizophrenia do not target …
adults diagnosed with schizophrenia, current treatments for schizophrenia do not target …
Transcriptional level of inflammation markers associates with short-term brain structural changes in first-episode schizophrenia
Background Inflammation has been implicated in the pathology of schizophrenia and may
cause neuronal cell death and dendrite loss. Neuroimaging studies have highlighted …
cause neuronal cell death and dendrite loss. Neuroimaging studies have highlighted …
[HTML][HTML] Neurobiologically based stratification of recent-onset depression and psychosis: identification of two distinct transdiagnostic phenotypes
Background Identifying neurobiologically based transdiagnostic categories of depression
and psychosis may elucidate heterogeneity and provide better candidates for predictive …
and psychosis may elucidate heterogeneity and provide better candidates for predictive …
Cognition in Patients with Schizophrenia: Interplay between Working Memory, Disorganized Symptoms, Dissociation, and the Onset and Duration of Psychosis, as …
G Panov, S Dyulgerova, P Panova - Biomedicines, 2023 - mdpi.com
Schizophrenia is traditionally associated with the presence of psychotic symptoms. In
addition to these, cognitive symptoms precede them and are present during the entire …
addition to these, cognitive symptoms precede them and are present during the entire …
The potential of precision psychiatry: what is in reach?
L Kambeitz-Ilankovic, N Koutsouleris… - The British Journal of …, 2022 - cambridge.org
Progress in developing personalised care for mental disorders is supported by numerous
proof-of-concept machine learning studies in the area of risk assessment, diagnostics and …
proof-of-concept machine learning studies in the area of risk assessment, diagnostics and …
Inflammatory disequilibrium and lateral ventricular enlargement in treatment-resistant schizophrenia
W Chen, M Gou, L Wang, N Li, W Li, J Tong… - European …, 2023 - Elsevier
Abstract Treatment-resistant schizophrenia (TRS) patient respond poorly to antipsychotics.
Inflammatory imbalance involving pro-and anti-inflammatory cytokines may play an …
Inflammatory imbalance involving pro-and anti-inflammatory cytokines may play an …
Effect of serum concentrations of IL-6 and TNF-α on brain structure in anorexia nervosa: a combined cross-sectional and longitudinal study
Previous studies of brain structure in anorexia nervosa (AN) have reported reduced gray
matter in underweight patients, which largely normalizes upon weight gain. One underlying …
matter in underweight patients, which largely normalizes upon weight gain. One underlying …
Investigation of choroid plexus variability in schizophrenia-spectrum disorders—insights from a multimodal study
Previous studies have suggested that choroid plexus (ChP) enlargement occurs in
individuals with schizophrenia-spectrum disorders (SSD) and is associated with peripheral …
individuals with schizophrenia-spectrum disorders (SSD) and is associated with peripheral …