Hypoxic ischemic brain injury (HIBI) after cardiac arrest (CA) is a leading cause of mortality
and long-term neurologic disability in survivors. The pathophysiology of HIBI encompasses …

Background Remote ischemic conditioning (RIC) is a noninvasive therapeutic strategy that
uses brief cycles of blood pressure cuff inflation and deflation to protect the myocardium …

We sought to review the role that cerebral edema plays in neurologic outcome following
cardiac arrest, to understand whether cerebral edema might be an appropriate therapeutic …

Cerebral ischemia/reperfusion (I/R) injury is a clinical event associated with high morbidity
and mortality. Neuroinflammation plays a crucial role in the pathogenesis of I/R‐induced …

Cardiac arrest has many implications for morbidity and mortality. Few interventions have
been shown to improve return of spontaneous circulation (ROSC) and long‐term outcomes …

Return of spontaneous circulation after cardiac arrest results in a systemic inflammatory
state called the post-cardiac arrest syndrome, which is characterized by oxidative stress …

Abstract β-Caryophyllene (BCP) has been reported to be protective against focal cerebral
ischemia–reperfusion (I/R) injury by its anti-oxidative and anti-inflammatory features. Recent …

Objective Assess whether elevated oxygen partial arterial pressure (PaO2) measured after
the initiation of extra-corporeal cardiopulmonary resuscitation (eCPR), is associated with …

In recent years, the use of thrombolytic therapy for treating ischemia/reperfusion injury has
resulted in damage to the self‑regulatory mechanisms of the brain. This is due to the …

Objective To systematically review the effectiveness and safety of intravascular temperature
management (IVTM) vs. surface cooling methods (SCM) for induced hypothermia (IH) …