Sialic acid receptors of viruses

M Matrosovich, G Herrler, HD Klenk - … chemistry and biology II: tools and …, 2015 - Springer
Sialic acid linked to glycoproteins and gangliosides is used by many viruses as a receptor
for cell entry. These viruses include important human and animal pathogens, such as …

A critical review of methods for detecting human noroviruses and predicting their infectivity

A Knight, D Li, M Uyttendaele… - Critical Reviews in …, 2013 - Taylor & Francis
Human noroviruses (hNoVs) are the single most common cause of acute non-bacterial
gastroenteritis in the industrialized world but cannot be grown in simple culture systems …

A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity

W Salmen, L Hu, M Bok, N Chaimongkol… - Nature …, 2023 - nature.com
Acute gastroenteritis caused by human noroviruses (HuNoVs) is a significant global health
and economic burden and is without licensed vaccines or antiviral drugs. The GII. 4 HuNoV …

Norwalk virus minor capsid protein VP2 associates within the VP1 shell domain

S Vongpunsawad, BV Venkataram Prasad… - Journal of …, 2013 - Am Soc Microbiol
The major capsid protein of norovirus VP1 assembles to form an icosahedral viral particle.
Despite evidence that the Norwalk virus (NV) minor structural protein VP2 is present in …

Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor

CA Nelson, CB Wilen, YN Dai… - Proceedings of the …, 2018 - National Acad Sciences
Murine norovirus (MNoV) is closely related to human norovirus (HNoV), an infectious agent
responsible for acute gastroenteritis worldwide. Here we report the X-ray crystal structure of …

Atomic structure of the predominant GII. 4 human norovirus capsid reveals novel stability and plasticity

L Hu, W Salmen, R Chen, Y Zhou, F Neill… - Nature …, 2022 - nature.com
Human noroviruses (HuNoVs) cause sporadic and epidemic viral gastroenteritis worldwide.
The GII. 4 variants are responsible for most HuNoV infections, and GII. 4 virus-like particles …

Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography

X Wang, F Xu, J Liu, B Gao, Y Liu, Y Zhai, J Ma… - PLoS …, 2013 - journals.plos.org
Rabbit hemorrhagic disease, first described in China in 1984, causes hemorrhagic necrosis
of the liver. Its etiological agent, rabbit hemorrhagic disease virus (RHDV), belongs to the …

Protruding Domain of Capsid Protein Is Necessary and Sufficient To Determine Murine Norovirus Replication and Pathogenesis In Vivo

DW Strong, LB Thackray, TJ Smith, HW Virgin - Journal of virology, 2012 - Am Soc Microbiol
Human noroviruses (HuNoVs) are the major cause of epidemic, nonbacterial gastroenteritis
worldwide. Due to the lack of a tractable model system and the inability to grow HuNoVs in …

Bile salts alter the mouse norovirus capsid conformation: possible implications for cell attachment and immune evasion

MB Sherman, AN Williams, HQ Smith, C Nelson… - Journal of …, 2019 - Am Soc Microbiol
Caliciviruses are single-stranded RNA viruses with 180 copies of capsid protein comprising
the T= 3 icosahedral capsids. The main capsid feature is a pronounced protruding (P) …

Nanobody binding to a conserved epitope promotes norovirus particle disassembly

AD Koromyslova, GS Hansman - Journal of virology, 2015 - Am Soc Microbiol
Human noroviruses are icosahedral single-stranded RNA viruses. The capsid protein is
divided into shell (S) and protruding (P) domains, which are connected by a flexible hinge …