Hydroxycamptothecin (HCPT) is a natural plant alkaloid from Camptotheca that shows
potent antitumor activity by targeting intracellular topoisomerase I. However, factors such as …

Selenium nanoparticles loaded with an anticancer molecule offer a new strategy for cancer
treatment. In the current study, anisomycin-loaded functionalized selenium nanoparticles …

In this study, a novel linolenic acid-modified poly (ethylene glycol)-b-poly (ϵ-caprolactone)
copolymer was prepared through radical addition, ring-opening polymerization, and N …

Amphiphilic poly (ethylene glycol)-imino-poly (benzyl-l-aspartate)(PIPA) and poly (ethylene
glycol)-poly (benzyl-l-aspartate)(PPA) block copolymers were synthesized as pH-responsive …

Due to the unsatisfactory therapeutic efficacy and inexorable side effects of small molecule
antineoplastic agents, extensive efforts have been devoted to the development of more …

Local extravasation and triggered drug delivery by use of ultrasound and microbubbles is a
promising strategy to target drugs to their sites of action. In the past we have developed drug …

The seeds of tree peony (Paeonia ostii) are promulgated as emerging edible oil crops.
However, biological properties of principal constituents of peony seeds were not well …

Supramolecular polymers formed through host–guest complexation have inspired many
interesting developments of functional materials for biological and biomedical applications …

As the central cellular player in fibrogenesis, activated hepatic stellate cells (aHSCs) are the
major target of antifibrotic nanomedicines. Based on our finding that activated HSCs …

Nostoc commune Vauch. has been traditionally used as a healthy food and medicine for
centuries especially in China. It has been demonstrated that the polysaccharides isolated …