[HTML][HTML] The role of VCP mutations in the Spectrum of amyotrophic lateral sclerosis—frontotemporal dementia
E Scarian, G Fiamingo, L Diamanti, I Palmieri… - Frontiers in …, 2022 - frontiersin.org
Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are two
neurological diseases which, respectively, and primarily affect motor neurons and …
neurological diseases which, respectively, and primarily affect motor neurons and …
[HTML][HTML] Diffusion tensor imaging in amyotrophic lateral sclerosis: machine learning for biomarker development
Diffusion tensor imaging (DTI) allows the in vivo imaging of pathological white matter
alterations, either with unbiased voxel-wise or hypothesis-guided tract-based analysis …
alterations, either with unbiased voxel-wise or hypothesis-guided tract-based analysis …
[HTML][HTML] Lipidomics study of plasma from patients suggest that ALS and PLS are part of a continuum of motor neuron disorders
Motor neuron disorders (MND) include a group of pathologies that affect upper and/or lower
motor neurons. Among them, amyotrophic lateral sclerosis (ALS) is characterized by …
motor neurons. Among them, amyotrophic lateral sclerosis (ALS) is characterized by …
Adaptive functional reorganization in amyotrophic lateral sclerosis: coexisting degenerative and compensatory changes
M Abidi, G de Marco, A Couillandre… - European Journal of …, 2020 - Wiley Online Library
Background and purpose Considerable functional reorganization takes place in
amyotrophic lateral sclerosis (ALS) in face of relentless structural degeneration. This study …
amyotrophic lateral sclerosis (ALS) in face of relentless structural degeneration. This study …
[HTML][HTML] Development and validation of a 1-year survival prognosis estimation model for Amyotrophic Lateral Sclerosis using manifold learning algorithm UMAP
Abstract Amyotrophic Lateral Sclerosis (ALS) is an inexorably progressive
neurodegenerative condition with no effective disease modifying therapies. The …
neurodegenerative condition with no effective disease modifying therapies. The …
[HTML][HTML] Pathological neural networks and artificial neural networks in ALS: diagnostic classification based on pathognomonic neuroimaging features
P Bede, A Murad, O Hardiman - Journal of neurology, 2021 - Springer
The description of group-level, genotype-and phenotype-associated imaging traits is
academically important, but the practical demands of clinical neurology centre on the …
academically important, but the practical demands of clinical neurology centre on the …
Hippocampal pathology in amyotrophic lateral sclerosis: selective vulnerability of subfields and their associated projections
F Christidi, E Karavasilis, M Rentzos, G Velonakis… - Neurobiology of …, 2019 - Elsevier
Although hippocampal involvement in amyotrophic lateral sclerosis (ALS) has been
consistently highlighted by postmortem studies, memory impairment remains under …
consistently highlighted by postmortem studies, memory impairment remains under …
The clinical and radiological profile of primary lateral sclerosis: a population-based study
Background Primary lateral sclerosis is a progressive upper-motor-neuron disorder
associated with markedly longer survival than ALS. In contrast to ALS, the genetic …
associated with markedly longer survival than ALS. In contrast to ALS, the genetic …
[HTML][HTML] Tracking a fast-moving disease: longitudinal markers, monitoring, and clinical trial endpoints in ALS
RH Chipika, E Finegan, S Li Hi Shing… - Frontiers in …, 2019 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) encompasses a heterogeneous group of phenotypes
with different progression rates, varying degree of extra-motor involvement and divergent …
with different progression rates, varying degree of extra-motor involvement and divergent …
[HTML][HTML] Amygdala pathology in amyotrophic lateral sclerosis and primary lateral sclerosis
Temporal lobe studies in motor neuron disease overwhelmingly focus on white matter
alterations and cortical grey matter atrophy. Reports on amygdala involvement are …
alterations and cortical grey matter atrophy. Reports on amygdala involvement are …