Impaired dopamine metabolism in Parkinson's disease pathogenesis
A full understanding of Parkinson's Disease etiopathogenesis and of the causes of the
preferential vulnerability of nigrostriatal dopaminergic neurons is still an unsolved puzzle. A …
preferential vulnerability of nigrostriatal dopaminergic neurons is still an unsolved puzzle. A …
Preventing Parkinson's disease: an environmental agenda
BR De Miranda, SM Goldman… - Journal of …, 2022 - content.iospress.com
Fueled by aging populations and continued environmental contamination, the global burden
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …
Epidemiology of Parkinson's disease
A Elbaz, L Carcaillon, S Kab, F Moisan - Revue neurologique, 2016 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's. PD is considered a multifactorial disorder that results, in most cases, from the …
Alzheimer's. PD is considered a multifactorial disorder that results, in most cases, from the …
Association between Parkinson's disease and cigarette smoking, rural living, well-water consumption, farming and pesticide use: systematic review and meta-analysis
CB Breckenridge, C Berry, ET Chang, RL Sielken Jr… - PloS one, 2016 - journals.plos.org
Objective Bradford Hill's viewpoints were used to conduct a weight-of-the-evidence
assessment of the association between Parkinson's disease (PD) and rural living, farming …
assessment of the association between Parkinson's disease (PD) and rural living, farming …
Environment, lifestyle, and Parkinson's disease: implications for prevention in the next decade
C Marras, CG Canning, SM Goldman - Movement Disorders, 2019 - Wiley Online Library
There is evidence from observational studies for a role of a number of environmental
exposures and lifestyle habits in modulating the risk for Parkinson's disease. Environmental …
exposures and lifestyle habits in modulating the risk for Parkinson's disease. Environmental …
Oxidative stress and neuroinflammation in Parkinson's disease: the role of dopamine oxidation products
S Chakrabarti, M Bisaglia - Antioxidants, 2023 - mdpi.com
Parkinson's disease (PD) is a chronic neurodegenerative condition affecting more than 1%
of people over 65 years old. It is characterized by the preferential degeneration of …
of people over 65 years old. It is characterized by the preferential degeneration of …
Overlapping neuroimmune mechanisms and therapeutic targets in neurodegenerative disorders
Many potential immune therapeutic targets are similarly affected in adult-onset
neurodegenerative diseases, such as Alzheimer's (AD) disease, Parkinson's disease (PD) …
neurodegenerative diseases, such as Alzheimer's (AD) disease, Parkinson's disease (PD) …
DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function
N Plotegher, G Berti, E Ferrari, I Tessari, M Zanetti… - Scientific reports, 2017 - nature.com
Parkinson's disease is a neurodegenerative disorder characterized by the death of
dopaminergic neurons and by accumulation of alpha-synuclein (aS) aggregates in the …
dopaminergic neurons and by accumulation of alpha-synuclein (aS) aggregates in the …
Pesticide use and incident Parkinson's disease in a cohort of farmers and their spouses
Background Extensive literature suggests an association between general pesticide use
and Parkinson's disease (PD). However, with few exceptions, little is known about …
and Parkinson's disease (PD). However, with few exceptions, little is known about …
Catecholamine autotoxicity. Implications for pharmacology and therapeutics of Parkinson disease and related disorders
DS Goldstein, IJ Kopin, Y Sharabi - Pharmacology & therapeutics, 2014 - Elsevier
Several neurodegenerative diseases involve loss of catecholamine neurons—Parkinson
disease is a prototypical example. Catecholamine neurons are rare in the nervous system …
disease is a prototypical example. Catecholamine neurons are rare in the nervous system …