Functional magnetic resonance spectroscopy (fMRS) can be used to investigate
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …

Animal and human postmortem studies provide evidence for changes in gamma-
aminobutyric acid (GABA) and glutamate in prefrontal cortex (PFC) during adolescence …

Anxious individuals consistently fail in controlling emotional behavior, leading to excessive
avoidance, a trait that prevents learning through exposure. Although the origin of this failure …

There has been little analysis of neurochemical correlates of compulsive behaviour to
illuminate its underlying neural mechanisms. We use 7-Tesla proton magnetic resonance …

Abstract Gamma-aminobutyric acid (GABA), the most important inhibitory neurotransmitter in
the human brain, has long been considered essential in human behavior in general and …

α-Asaronol from Acorus tatarinowii (known as “Shichangpu” in Traditional Chinese
medicine) has been proved to possess more efficient antiepileptic activity and lower toxicity …

Background Numerous magnetic resonance spectroscopy (MRS) studies have reported
metabolic abnormalities in the brains of patients with depression, although inconsistent …

INTRODUCTION Accumulation and interaction of amyloid‐beta (Aβ) and tau proteins during
progression of Alzheimer's disease (AD) are shown to tilt neuronal circuits away from …

Equilibrium between excitation and inhibition (E/I balance) is key to healthy brain function.
Conversely, disruption of normal E/I balance has been implicated in a range of central …

Theoretical work, supported by electrophysiological evidence, asserts that a balance
between excitation and inhibition (E/I) is critical for healthy brain function. In magnetic …